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Moumoujus

MYRISTOYL OCTAPEPTIDE-1.

Valuable CAS - / SKIN CONDITIONING

Myristoyl Octapeptide-1 is a synthetic lipo-peptide engineered to mimic key growth factors, thereby stimulating intrinsic skin repair processes. It actively promotes the densification of both epidermal and dermal layers, leading to enhanced skin firmness and rejuvenation.

Summary

Mimics Growth Factors Promotes Dermal Tissue Repair Accelerates Wound Healing Boosts Fibroblast Proliferation Enhances Epidermal Densification Enhances Dermal Densification Supports Matrix Remodeling Strengthens Dermal-Epidermal Junction Upregulates Growth Factors (IGF, HGF) Stimulates Cell Metabolism Supports Cellular Regeneration Reduces Appearance of Wrinkles Improves Skin Texture Enhances Skin Firmness Boosts Skin Elasticity Improves Skin Smoothness Enhances Skin Hydration

Science

Mechanism of Action

This synthetic lipo-peptide functions by specifically engaging receptors on fibroblasts, the skin's vital matrix-producing cells. This interaction triggers a cascade of cellular events, including increased fibroblast proliferation and differentiation, ultimately boosting skin cell activity. Myristoyl Octapeptide-1 is instrumental in promoting matrix remodeling and accelerating tissue repair, leading to a noticeable densification of both the epidermis and dermis through an increase in cell layers. It also plays a crucial role in rejuvenating the basement membrane by enhancing fibroblast synthesis, thereby strengthening the structural integrity between skin layers. Furthermore, it upregulates essential growth factors like insulin-like growth factor (IGF) and human growth factor (HGF), critical for maintaining robust cellular health, efficient communication, and overall metabolic repair functions within the skin.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Possessing an amphiphilic nature, Myristoyl Octapeptide-1 exhibits good solubility in organic solvents, notably approximately 30 mg/ml in dimethyl sulfoxide (DMSO) and readily in ethanol. Its aqueous solubility is limited, typically necessitating co-solvents or surfactants for adequate dispersion. In its white powder form, it maintains stability when stored in a cool, dry environment between 2-8°C, protected from light, with long-term viability extending beyond 4 years at -20°C to -15°C. However, its stability in aqueous solutions is significantly reduced, degrading within 24 hours.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

This peptide is generally considered safe and effective for topical application. It has been tested and found to be free from heavy metals and potential skin or eye irritants.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Myristoyl Octapeptide-1 is a valuable lipo-peptide that precisely targets fibroblast activity and growth factors to promote skin densification, repair, and overall cellular rejuvenation.

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