Science
Mechanism of Action
This ingredient functions as a potent antioxidant, neutralizing free radicals and combating oxidative stress through its abundance of anthocyanins, flavonoids, and vitamin C. It actively soothes skin and reinforces defense against oxidative damage. Furthermore, it exhibits anti-melanogenesis properties by inhibiting melanin synthesis and tyrosinase activity, concurrently down-regulating MITF and TRP-1 gene expression and protein secretion. Its benefits extend to interrupting pathways linked to acne inflammation and playing a role in mitigating glycation, while also supporting enzymatic antioxidant activities such as SOD, GPx, and MDA.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 At concentrations of 5-10%, Myrica Rubra Fruit Juice is recommended for its ability to soothe irritation and calm dry, sensitive skin.
- 02 In vitro studies on its water extract have demonstrated significant inhibition of melanin synthesis and tyrosinase activity, down-regulation of MITF and TRP-1 gene and protein expression, and potent scavenging of DPPH free radicals while suppressing ROS production in melanoma cell lines.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The phytochemical integrity of Myrica Rubra Fruit Juice can be compromised during initial processing steps, such as blanching, crushing, pasteurization, and depectinization, leading to a significant reduction in total polyphenolics and anthocyanins. Phenolics and flavonoids within the juice may also complex with polysaccharides, influenced by their water solubility, molecular size, conformational mobility, and structure.
Safety
Safety Profile
While the Cosmetic Ingredient Review (CIR) has 'insufficient data' for a full safety assessment, the ingredient does not have a GHS classification for hazards. Oral, Dermal, and Inhalation Toxicity data for Myrica Rubra Fruit Juice specifically are not determined. However, a water extract of Myrica rubra fruit has demonstrated safety in studies evaluating its melanin inhibitory and antioxidant effects. It is also recognized by the FDA as a food additive.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Myrica Rubra Fruit Juice is a valuable multi-functional ingredient, offering significant antioxidant, soothing, brightening, and anti-inflammatory benefits across all skin types, despite pending comprehensive CIR safety data.
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