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Moumoujus

MYRETH-10.

Valuable CAS 27306-79-2 / SURFACTANT - EMULSIFYING

MYRETH-10 is a versatile, alkoxylated diester emollient that excels in aqueous systems. It conditions both skin and hair, effectively solubilizes oils and fragrances, and significantly reduces irritation commonly associated with surfactants, delivering a smooth, non-greasy feel.

Summary

Emollient Skin conditioning Surfactant Solubilizer

Science

Mechanism of Action

Operating as a multifunctional diester, MYRETH-10 integrates into cosmetic formulations as a water-dispersible and surfactant-compatible agent. Its primary mechanism involves reducing the surface tension of products for improved distribution, while simultaneously conditioning the skin by softening its texture and enhancing moisture retention through evaporation prevention. It actively mitigates the harsh effects of other surfactants, thereby decreasing their potential to induce irritation.

Research

Clinical Evidence

High confidence
Effective range 1–10%
Optimal

5%

Key findings

  1. 01 At a 5% concentration, MYRETH-10 has been demonstrated to reduce surfactant-induced irritation by up to 40% (SpecialChem).
  2. 02 In controlled laboratory models, 5% MYRETH-10 significantly decreased SLS-induced cell death by 30% in the EpiOcular™ Model and lowered irritation potential in the TransEpithelial Permeability Model when co-formulated with 10% SLS (Mattek - Part of Sartorius).
  3. 03 Further studies indicated that concentrations of 1%, 5%, and 10% reduced the irritation caused by 1% SLS to a level comparable to distilled water in 75% of human subjects (Mattek - Part of Sartorius).
  4. 04 Notably, when applied at 100% concentration, MYRETH-10 was found to be less irritating than distilled water itself (Mattek - Part of Sartorius).

Transparency

Dusting Analysis

Not commonly dusted

MYRETH-10 is presented as a clear, low-viscosity liquid, indicating it is not a particulate ingredient prone to dusting. Its formulation characteristics align with easy integration into various cosmetic systems.

The Formula

Formulation

Solubility
Both
Optimal pH 5 – 7
0 7 14

Stability

A clear, low-viscosity liquid, MYRETH-10 maintains optimal stability and efficacy within a pH range of 5.0 to 7.0. It exhibits broad compatibility, integrating effectively into both clear systems and emulsion-based products like creams and lotions. This ingredient can be incorporated into the heated oil phase, processed cold, or directly added to the water phase in formulations lacking an oil component.

Synergies

  • Enhances mildness and user comfort in formulations containing other surfactants by actively mitigating irritation.
  • Improves the solubilization of oils and fragrances within aqueous systems, facilitating the creation of stable and clear product formulations.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
10%
Sensitization risk Low

MYRETH-10 is widely considered safe for cosmetic use, demonstrating a consistently low irritation potential. It is approved by the EU COSING database for its skin conditioning and emollient functions. While some assessments note a moderate hazard rating due to general ethoxylation concerns, modern production processes are designed to minimize residual impurities effectively. It is absent from EWG's Skin Deep Restricted or Unacceptable Lists, and SkinSAFE rigorously categorizes it as Teen SAFE, Lip SAFE, Baby SAFE, Eyelid SAFE, Irritant Free, Dye Free, SLS Free, and Non-Comedogenic. Maximum typical use levels range from 1% to 10%, though some product types may utilize up to 25%.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

MYRETH-10 is a valuable, multifunctional ingredient, particularly for precision cleansing and conditioning formulations, offering proven irritation mitigation and enhanced sensory attributes across all skin types.

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