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MUSK R1.

Questionable CAS 3391-83-1 / PERFUMING

MUSK R1 is a synthetic macrocyclic musk compound primarily utilized as a fragrance ingredient in cosmetics. It imparts a creamy, powdery, and warm skin-like scent, designed to add depth and enhance the longevity of fragrance compositions without contributing heaviness.

fragrance_ingredient perfuming

Science

MUSK R1's mechanism of action is solely as a perfuming agent, contributing a specific scent profile to formulations. There is no documented evidence or mechanism for it providing active skincare benefits to the skin.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Commonly dusted

MUSK R1 serves exclusively as a fragrance component, with no documented active benefits for skin health. Its inclusion in a precision skincare product would be for sensorial experience rather than therapeutic effect.


The Formula

Solubility
Oil
Optimal pH 3 – 9
0 7 14

Stability

MUSK R1 maintains its olfactory profile effectively within a pH range of 3.0 to 9.0. Odor performance may diminish outside this range, particularly at pH 2 or pH 10-11. The material is stable under typical storage conditions; extreme heat should be avoided.

Conflicts

  • strong acids
  • alkalis
  • strong oxidizing agents

Safety

CIR Status
Not reviewed
Max tested
10%
Sensitization risk Low

Although not reviewed by CIR, MUSK R1 is permitted up to 10% concentration and is not anticipated to cause skin sensitization. It may cause mild skin irritation (H316). It adheres to IFRA 51st amendment (Category 4) and EU 1223/2009 cosmetic regulations.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Questionable

As MUSK R1 provides no documented active skincare benefits and carries a potential for mild irritation, its inclusion in precision skincare formulations is questionable for efficacy-driven purposes, primarily serving a purely sensorial role.


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