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Moumoujus

MURRAYA KOENIGII STEM EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Murraya Koenigii Stem Extract is a botanical active renowned for its multi-functional benefits in skincare. It conditions the skin, enhancing softness and suppleness, while actively targeting visible signs of aging by boosting skin elasticity and firmness.

Summary

Skin-conditioning Antioxidant Anti-aging Elasticity booster Anti-inflammatory Antimicrobial Firming Barrier support Anti-sagging

Science

Mechanism of Action

This extract operates on multiple levels to support skin health and combat aging. Its rich composition of bioactive compounds, including alkaloids, flavonoids, and glycosides, provides antioxidant, anti-inflammatory, and antimicrobial properties. Crucially, it stimulates the expression of key proteins vital for functional elastic fiber synthesis and maintenance, such as elastin, fibrillin-1, fibrillin-2, and fibulin-5. This action improves skin elasticity, firmness, and overall structural integrity, helping to densify the extracellular matrix (ECM) to combat sagging and protect against oxidative stress while reinforcing the skin's natural barrier.

Research

Clinical Evidence

High confidence
Effective range 0.1–10%
Optimal

0.5%

Key findings

  1. 01 A 98-day clinical study utilizing a 1% concentration, applied twice daily, demonstrated a visible reduction in the severity of nasogenian folds and jowls, effectively mitigating the gravitational impact on facial aging. This was supported by increased protein expressions of elastin and fibrillin-1, leading to enhanced tissue elasticity.
  2. 02 Further research indicates that concentrations ranging from 0.1% to 10% are effective for improving skin appearance, preserving and enhancing elasticity, and combating both intrinsic and extrinsic skin aging, including photoaging. Optimal efficacy for these benefits is suggested within the 0.5% to 5% range.

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
0.1%

Effective concentrations for skin improvement and elasticity benefits begin at 0.1%. For optimal anti-aging and skin elasticity outcomes, a concentration between 0.5% and 5% is recommended. Formulations containing less than 0.1% are unlikely to yield significant clinical results.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

For topical skin applications, the extract is best formulated in products with a pH close to the skin's natural acidity (approximately pH 5.5) or neutral. Its diverse solubility in various solvents (e.g., ethanol, water) indicates that different active components can be extracted and formulated depending on the desired polarity.

Conflicts

  • High concentrations of alkaloids (above 5 mg/100 g of extract) due to potential toxicity

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Side effects from Murraya Koenigii Stem Extract are relatively uncommon, though a preliminary patch test is always advisable. Data on its topical usage during pregnancy and breastfeeding is currently insufficient, necessitating consultation with a healthcare professional. While its active principles are generally biocompatible, cosmetic formulations should contain an extract with trace amounts of alkaloids, ideally less than 5 mg/100 g, to mitigate potential toxicity risks associated with purified alkaloid forms. Its historical use in food suggests a generally safe profile.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Murraya Koenigii Stem Extract is a valuable botanical ingredient offering robust anti-aging and elasticity-boosting benefits through its multifaceted action on skin proteins and matrix densification, with a favorable safety and compatibility profile.

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