Science
Mechanism of Action
This essential oil exerts its anti-inflammatory effects through the inhibition of pro-inflammatory cytokines and enzymes like COX-2 and iNOS. Its potent antioxidant capacity stems from its ability to scavenge superoxide and hydroxyl radicals, inhibit xanthine oxidase activity, and prevent lipid peroxidation. Furthermore, it possesses antibacterial, antifungal, and anticarcinogenic properties, aiding in skin healing, mitigating damage from pollution and environmental stress, and reducing the visibility of scars and blemishes.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Demonstrated superior inhibition of lipid peroxidation when compared to 0.01% BHT, indicating its robust antioxidant capabilities.
- 02 The essential oil exhibited a significant antioxidant effect with an IC50 (concentration for 50% inhibition) of 0.29 µg/mL. Linalool, a primary component (at 0.6 μg/mL), achieved 91.20% inhibition of hydroxyl radicals, while the essential oil itself showed 87.27% inhibition with increasing concentration.
- 03 Effectively inhibited the proliferation of various bacteria, including Staphylococcus aureus, Escherichia coli, and Salmonella typhi.
- 04 Murraya koenigii oleoresin exhibited 83.2% antioxidant activity.
Transparency
Dusting Analysis
Murraya Koenigii Leaf Oil functions as a multi-active ingredient, valued for its specific biological effects rather than merely contributing to the bulk or sensory profile of a formulation.
The Formula
Formulation
Stability
As an essential oil, it consists of volatile compounds. No specific optimal pH range for its stability was identified in the research. It is crucial to dilute this oil with a suitable carrier oil prior to topical application.
Safety
Safety Profile
The RIFM Fragrance Material Safety Assessment recommends usage levels for fragrance concentrates up to 2.0000%. It is important to note the presence of farnesol (found at <0.40% max) and geraniol (found at <0.60% max), which are restricted components due to their potential for sensitization. Despite this, a face wash formulation containing curry leaf was found to be safe and non-irritant. Nature In Bottle certifies this oil as suitable for cosmetic applications and confirms its compliance with EU Regulation (EC) No 1223/2009 regarding prohibited cosmetic substances.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Murraya Koenigii Leaf Oil is a valuable ingredient, delivering significant antioxidant, anti-inflammatory, and antimicrobial benefits suitable for all skin types, with a low risk of irritation and comedogenicity within recommended usage concentrations.
Related
Similar Ingredients
Finding similar ingredients…