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Moumoujus

MOSLA DIANTHERA EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Mosla Dianthera Extract is a botanical ingredient distinguished by its robust antioxidant and anti-inflammatory properties. It actively neutralizes various free radicals and modulates inflammatory pathways, making it particularly beneficial for calming and protecting stressed skin. Traditionally recognized for its soothing effects, it offers a multi-faceted approach to skin resilience.

Summary

Antioxidant Anti-inflammatory Soothing Anti-allergic

Science

Mechanism of Action

Mosla Dianthera Extract operates through a comprehensive defense mechanism, effectively scavenging a broad spectrum of reactive species, including DPPH, hydroxyl, nitric oxide, and superoxide radicals. Its demonstrated reducing power and metal chelating capabilities further bolster its antioxidant capacity. Concurrently, it exerts potent anti-inflammatory and anti-allergic effects by inhibiting albumin denaturation and suppressing histamine release and pro-inflammatory cytokine production in mast cells, thereby reducing skin reactivity.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Demonstrated potent in vitro DPPH radical scavenging activity at an IC50 of 169.56 µg/mL.
  2. 02 Exhibited strong in vitro hydroxyl radical scavenging activity with an IC50 of 124.66 µg/mL.
  3. 03 Showed significant in vitro nitric oxide radical scavenging activity, achieving an IC50 of 144.78 µg/mL.
  4. 04 Proved effective in in vitro superoxide radical scavenging, with an IC50 of 132.44 µg/mL.
  5. 05 Displayed in vitro reducing power activity at an RP50 of 204.21 µg/mL.
  6. 06 Possessed in vitro metal chelating activity at an IC50 of 231.81 µg/mL.
  7. 07 Exhibited in vitro anti-inflammatory activity through inhibition of albumin denaturation at an IC50 of 120.83 µg/mL.
  8. 08 Inhibits mast cell-mediated allergic reactions by suppressing histamine release and inflammatory cytokine production, indicating anti-allergic and anti-inflammatory properties.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

No specific optimal pH range for stability in cosmetic formulations has been identified. Its diverse chemical composition suggests components may exhibit varied solubility, with essential oil constituents being oil-soluble and phenolic compounds potentially soluble in water or hydroalcoholic systems.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No formal safety assessments by major regulatory bodies such as CIR, SCCS, or FDA specifically for cosmetic applications of Mosla Dianthera Extract were found in the provided data. Comprehensive toxicological and dermatological safety profiles are yet to be established for widespread cosmetic use.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Mosla Dianthera Extract demonstrates compelling in vitro antioxidant and anti-inflammatory efficacy, positioning it as a valuable ingredient for sensitive and reactive skin, although further in vivo and regulatory safety data are needed to fully confirm its topical potential.

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References

Sources