Science
Mechanism of Action
This extract functions primarily as a powerful antioxidant, effectively neutralizing free radicals to protect the skin from environmental damage that leads to premature aging, fine lines, and wrinkles. It achieves skin brightening by inhibiting tyrosinase, the key enzyme in melanin synthesis, thereby reducing the appearance of dark spots. Anti-inflammatory actions, specifically through components like oxyresveratrol, are mediated via the MEK/ERK signaling pathway. Furthermore, it acts as an astringent to refine pore appearance and offers emollient and skin conditioning effects, forming a protective barrier to retain moisture and promote a smoother, more hydrated skin surface.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In vitro studies on Morus bombycis root extract demonstrated significant anti-lipase activity with an IC50 of 2.07 microg/mL, suggesting potential anti-obesity effects.
- 02 Morus bombycis root extract has been observed to display a skin whitening effect through the inhibition of tyrosinase.
Transparency
Dusting Analysis
The available research does not suggest this ingredient is commonly used at ineffective concentrations or is a candidate for 'dusting'.
The Formula
Formulation
Stability
Optimal stability and functional properties for related mulberry extracts are typically observed within a pH range of 4.0 to 6.0. Extracts from various mulberry species show good stability around pH 6.0 in emulsions, and an optimum pH of 4.0 has been noted for maximizing yield and antioxidant content in some leaf extracts. It is readily extracted and soluble in polar solvents such as water and alcohol.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has not formally reviewed Morus Bombycis Wood Extract, and its status is noted as 'Not rated' by Paula's Choice due to ongoing research evaluation. While side effects from Morus Bombycis Leaf/Root Extract are generally uncommon, patch testing is recommended prior to widespread use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Morus Bombycis Wood Extract is a valuable botanical offering comprehensive skin benefits, particularly its antioxidant, brightening, and conditioning properties, with a favorable safety and compatibility profile across all skin types.
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