Science
Mechanism of Action
Morus Alba Leaf Extract functions synergistically to improve skin health and appearance. Its primary mechanism involves the inhibition of tyrosinase, a crucial enzyme in melanin production, which effectively diminishes hyperpigmentation and dark spots. Furthermore, its abundant content of flavonoids, phenols, and anthocyanins provides robust antioxidant protection, neutralizing free radicals and mitigating oxidative stress to support anti-aging efforts. The extract also demonstrates anti-inflammatory properties, reducing redness and soothing skin, while contributing to the reinforcement of the skin's natural barrier. Minor antibacterial and antifungal benefits have also been observed.
Research
Clinical Evidence
High confidence2-10%
Key findings
- 01 Demonstrated significant reduction in melasma severity and melanin content, with only mild, infrequent itching reported, suggesting efficacy in targeted hyperpigmentation treatment.
- 02 Proven to decrease skin melanin content and reduce erythema, indicating effective skin brightening and anti-irritation benefits in a cream formulation.
- 03 Industry recommended use level for cosmetic applications, with 2-5% for general formulations and 5-10% for water/glycerin dissolved extracts, reflecting its versatile application range.
- 04 Exhibited potent anti-melanogenic and antioxidant activities by inhibiting melanin synthesis in B16F10 melanocytes, supporting its role in hyperpigmentation formulations.
Transparency
Dusting Analysis
No data available regarding 'dusting' of Morus Alba Leaf Extract in the provided research, therefore it is not classified as commonly dusted.
The Formula
Formulation
Stability
The extract, typically an aqueous solution in glycerin, exhibits stability across a pH range of 3.9 to 7.2. While hydro-alcoholic mixtures can enhance the extraction of some biomolecules, the cosmetic ingredient itself is primarily water-soluble.
Safety
Safety Profile
Generally regarded as safe for cosmetic applications, Morus Alba Leaf Extract is permitted by regulatory bodies like the European Union. Clinical observations indicate a low potential for irritation; for instance, a 75% concentration resulted in mild itching in a small subset of users, while a 4% cream was confirmed non-irritating. Acute oral toxicity studies in mice showed no adverse effects or genotoxicity. While comprehensive safety assessments by CIR or SCCS were not found, SkinSAFE lists it as 'Irritant Free'.
Your Skin
Skin Compatibility
Our Assessment
Verdict
With strong scientific backing for its skin-brightening, antioxidant, and anti-inflammatory properties at clinically relevant concentrations, Morus Alba Leaf Extract is a valuable and well-tolerated ingredient for a wide range of skin concerns.
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