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Moumoujus

MOMORDICA CHARANTIA STEM EXTRACT.

Valuable CAS 93333-80-3 / SKIN CONDITIONING

MOMORDICA CHARANTIA STEM EXTRACT is a potent botanical active celebrated for its extensive dermatological benefits, including robust antioxidant and anti-inflammatory actions. It significantly supports skin regeneration by enhancing collagen production and fibroblast migration, crucial for tissue repair. This versatile extract also provides conditioning, astringent, and anti-aging properties, addressing various concerns from acne to compromised skin elasticity.

Summary

Antioxidant Anti-inflammatory Antimicrobial Wound Healing Collagen Boosting Skin Conditioning Astringent Anti-aging Acne Management Cleansing Moisturizing Elasticity Enhancer Soothing

Science

Mechanism of Action

This extract operates through a multifaceted biological pathway, leveraging its inherent antioxidant, anti-inflammatory, and antimicrobial characteristics. It actively promotes skin healing by stimulating epithelialization, fostering neovascularization, and accelerating fibroblast proliferation and migration, which are key processes for collagen synthesis and tissue repair. Furthermore, it attenuates Propionibacterium acnes-induced inflammation, contributes to a cleaning effect by aiding in the removal of excess dead cells and sebum, and delivers moisturizing and nourishing compounds to enhance skin elasticity and provide anti-aging benefits.

Research

Clinical Evidence

Medium confidence
Effective range 1–5%
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

The extract comprises both water-soluble components, such as phenolic compounds, and fat-soluble constituents, including charantin and steroids. For initial extract stabilization, a pH range of 2.5-4, ideally 3.5-4.0, has been utilized before neutralization to a skin-compatible pH of 6.5-7.0. Formulated serums demonstrate excellent solubility, yielding homogeneous solutions with pH values within the skin-friendly range to minimize irritation.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While MOMORDICA CHARANTIA STEM EXTRACT lacks specific CIR, SCCS, or FDA review status, related Momordica charantia fruit extract has been determined non-phototoxic, non-irritating, and non-sensitizing in in vitro evaluations. Oral administration to rats indicated a low toxicity profile (LD50 >2,000 mg/kg). However, individuals with known allergies to the Cucurbitaceae plant family should avoid its use. Due to reports of abortive properties in animals from oral consumption of the general plant, caution is advised, and professional medical consultation is recommended for topical use during pregnancy.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

MOMORDICA CHARANTIA STEM EXTRACT is a valuable botanical ingredient, offering comprehensive benefits from advanced wound healing and collagen synthesis to anti-aging and acne management, suitable for diverse skin types.

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