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Moumoujus

MOMORDICA CHARANTIA FRUIT POWDER.

Valuable CAS 93333-80-3 / SKIN CONDITIONING

Momordica Charantia Fruit Powder, derived from bitter melon, is a multifaceted botanical ingredient offering significant skin benefits. Rich in phenolic antioxidants, it actively combats oxidative stress and helps regulate inflammatory pathways, promoting a calmer, more resilient complexion. It also supports skin regeneration and provides noticeable tightening effects at higher concentrations.

Summary

Antioxidant Anti-aging Soothing Astringent Wound healing Antibacterial Skin brightening (Tyrosinase inhibition) Anti-wrinkle (Elastase inhibition) Skin elasticity enhancement Collagen protection

Science

Mechanism of Action

This fruit powder delivers potent antioxidant protection through its phenolic compounds, effectively neutralizing free radicals responsible for oxidative stress and premature aging. It works to modulate inflammatory responses, contributing to a soothing effect on the skin. At concentrations around 3%, its astringent properties induce a temporary contraction of proteins in skin cells, resulting in a tightening sensation. Furthermore, it aids in skin repair by enhancing epithelialization, new blood vessel formation (neovascularization), and fibroblast proliferation, alongside its anti-inflammatory action. It can also help preserve collagen, boost skin elasticity, and exhibits antibacterial activity against common skin microbes like E. coli and S. aureus. Its capacity to inhibit tyrosinase suggests skin brightening benefits, while elastase inhibition points to anti-wrinkle efficacy.

Research

Clinical Evidence

Medium confidence
Effective range 1–3%
Optimal

3%

Key findings

  1. 01 Recommended use levels in cosmetics range from 1-3%.
  2. 02 Concentrations around 3% can produce a noticeable tightening sensation on the skin due to astringent properties.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 6.37 – 6.67
0 7 14

Stability

Natural extracts can exhibit inherent instability and limited bioavailability. To enhance stability and controlled release, incorporating Vitamin E oil, glycerin, or starch-based formulation systems is recommended. Solution formulations containing 5% extract demonstrated stability for 28 days. Cream formulations with 4% leaf extract maintained stability for 3 months within the optimal pH range of 6.37-6.67 at both room temperature and elevated temperatures (60°C).

Synergies

  • Vitamin E
  • Glycerin

Safety

Safety Profile

CIR Status
Not reviewed
Pregnancy
Safe
Sensitization risk Low

This ingredient is generally well-tolerated for topical use. Studies on its extract have shown no cell toxicity up to 1,000 µg/mL, no phototoxicity, no skin irritation in RHE tests, and no skin sensitization in local lymph node assays. SkinSAFE rates Momordica Charantia Fruit Extract as 'Teen SAFE' and free from common allergens. While some studies suggest caution for *internal* consumption in pregnant or breastfeeding individuals due to potential systemic effects, this concern is not applicable to typical cosmetic topical application.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Momordica Charantia Fruit Powder is a valuable botanical ingredient, offering comprehensive benefits from antioxidant and anti-inflammatory action to skin tightening and regenerative support for all skin types, with a favorable topical safety profile.

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