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MIYAMAYOMENA KORAIENSIS LEAF/STEM EXTRACT.

Valuable / SKIN CONDITIONING

MIYAMAYOMENA KORAIENSIS LEAF/STEM EXTRACT, derived from a plant akin to Aster koraiensis, is a multi-functional ingredient demonstrating potent anti-inflammatory, antioxidant, and skin-conditioning capabilities. It actively targets inflammatory pathways, mitigates oxidative stress, and supports overall skin health, making it suitable for a range of skin concerns.

Summary

Anti-inflammatory Antioxidant Skin Conditioning Anti-aging Moisturizing Brightening Sebum Regulating

Science

Mechanism of Action

This extract functions by modulating several key biological processes in the skin. It significantly reduces levels of pro-inflammatory cytokines such as TNF-α, IFN-γ, IL-1β, and IL-6, which are critical mediators in inflammatory skin conditions. Furthermore, it inhibits the activity of enzymes including cyclooxygenase (COX)-2, iNOS, tyrosinase, elastase, lipoxygenase, MMP-1, and MMP-3, thereby addressing inflammation, hyperpigmentation, collagen degradation, and excessive sebum production. Its antioxidant capacity is evidenced by its ability to scavenge DPPH radicals and increase ferric reducing antioxidant power (FRAP) and trolox equivalent antioxidant capacity (TEAC), protecting against oxidative damage. The extract may also support keratinocyte proliferation and promote Type 1 procollagen biosynthesis, contributing to skin barrier integrity and elasticity.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Specific optimal pH ranges for stability were not identified. Formulators should be aware that concentrations exceeding 25 weight percent, based on observations with Pinus koraiensis extract, might impact product feel and overall formulation stability. Extraction can be achieved using solvents such as 95% ethanol, water, low alcohols (C1-C3), acetone, ethyl acetate, or diethyl ether.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
500%
Sensitization risk Low

While not formally reviewed by CIR, SCCS, or FDA for cosmetic use, Aster koraiensis leaves are approved as edible material in South Korea. In vitro studies indicate no cytotoxicity up to 500 μg/mL, with potential cytotoxicity observed at very high concentrations (1000 μg/mL).

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

MIYAMAYOMENA KORAIENSIS LEAF/STEM EXTRACT is a valuable multi-active ingredient for precision skincare, offering scientifically-backed anti-inflammatory, antioxidant, and skin-conditioning benefits across all skin types with a low irritancy potential.

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