Science
Mechanism of Action
This extract actively promotes keratinocyte proliferation and migration, pivotal for skin repair and renewal, and stimulates the synthesis of type I and IV collagens. Its mechanism involves increasing the phosphorylation of key signaling proteins like serine/threonine-specific protein kinase, p38 mitogen-activated protein kinase, and extracellular signal-regulated kinase1/2 within keratinocytes. Furthermore, it demonstrates a capacity to decrease serum-induced melanoma cell proliferation and effectively inhibit tyrosinase activity and melanin production in α-MSH-stimulated melanoma cells, contributing to skin brightening. The presence of phenolic derivatives, including ferulic and p-coumaric acids, endows the extract with significant antioxidant capabilities, acting as reducing agents and singlet oxygen quenchers.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
Current safety data, as reviewed by CIR, is categorized as 'insufficient data.' No specific CIR, SCCS, or FDA safety assessment for Miscanthus Sinensis Flower Extract was found, implying a need for further comprehensive safety evaluations for cosmetic use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Miscanthus Sinensis Flower Extract presents as a valuable multi-active ingredient with promising in vitro and in vivo (mouse) data for skin regeneration, brightening, antioxidant protection, and hair growth, though human safety data is currently insufficient.
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References
Sources