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Moumoujus

MISCANTHUS SINENSIS EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Miscanthus Sinensis Extract is a multi-functional botanical ingredient derived from Japanese silvergrass. It demonstrates significant potential in skin revitalization by promoting collagen synthesis, supporting wound healing, reducing hyperpigmentation, and offering antioxidant and anti-inflammatory benefits for comprehensive skin support.

Summary

Skin conditioning Antioxidant Skin brightening Wound healing Collagen boosting Anti-inflammatory

Science

Mechanism of Action

This extract actively engages with skin at a cellular level. It stimulates the proliferation and migration of keratinocytes, which are crucial for skin repair, and enhances the synthesis of essential type I and IV collagens, vital for maintaining skin structure and elasticity. Its mechanism involves increasing the phosphorylation of key signaling proteins, including serine/threonine-specific protein kinase, p38 mitogen-activated protein kinase, and extracellular signal-regulated kinase1/2, within keratinocytes. Furthermore, it modulates melanogenesis by decreasing melanoma cell proliferation and inhibiting tyrosinase activity and melanin production in melanocytes. Miscanthus sinensis also contains hydroxycinnamates, recognized for their antioxidant properties, and has demonstrated anti-inflammatory effects by suppressing IgE-mediated reactions and inflammatory cells.

Research

Clinical Evidence

Medium confidence
Effective range 50 µg/mL (in vitro)–150 µg/mL (in vitro)%
Optimal

N/A

Key findings

  1. 01 At a concentration of 50 µg/mL, Miscanthus sinensis extract induced proliferation, migration, and the synthesis of type I and IV collagens in human keratinocytes.
  2. 02 Increasing the concentration to 150 µg/mL further stimulated proliferation, migration, and type I and IV collagen synthesis in human keratinocytes. Additionally, it decreased serum-induced melanoma cell proliferation and inhibited tyrosinase activity and melanin content in α-MSH-stimulated melanoma cells.

Transparency

Dusting Analysis

Not commonly dusted

Information regarding the 'dusting' potential or specific thresholds for Miscanthus Sinensis Extract is not available in the provided research. Moumoujus focuses on formulations with clearly established efficacy parameters.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Miscanthus Sinensis Extract exhibits complex solubility, with active components soluble in both water and polar organic solvents like methanol, indicating versatility in formulation. Specific optimal pH ranges for stability are not detailed. As with many botanical extracts, care should be taken to protect the formulation from light and oxygen exposure to maintain ingredient integrity and efficacy.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) has not specifically reviewed Miscanthus Sinensis Extract. However, its listing on COSMILE Europe as a skin conditioning agent suggests general acceptance for cosmetic use within the EU, which requires internal company safety assessments. No specific maximum concentration, detailed sensitization risk data, or pregnancy safety information were found in the provided research.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Miscanthus Sinensis Extract is a valuable multi-functional ingredient offering significant potential for skin repair, brightening, and anti-aging benefits, making it an excellent addition to targeted skincare formulations.

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