Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

MIRABILIS JALAPA SEED EXTRACT.

Valuable CAS 91722-88-2 / SKIN PROTECTING

Mirabilis Jalapa Seed Extract, derived from the 'Four O'Clock flower', is a multifaceted botanical ingredient designed to enhance skin resilience. It is recognized for its ability to soothe hypersensitive skin, reinforce the epidermal barrier, and deliver potent antioxidant and anti-inflammatory benefits.

Summary

Soothing Antioxidant Skin-protecting Skin conditioning Anti-inflammatory Brightening Anti-aging

Science

Mechanism of Action

This extract operates by modulating key skin pathways. It significantly reduces the overproduction of Nerve Growth Factor (NGF) and TRPV1 receptors, which are crucial mediators in skin sensitivity, thereby diminishing reactive responses. Concurrently, it strengthens the epidermal barrier and improves stratum corneum integrity, enhancing skin's natural defense. Its antioxidant capacity is driven by free radical scavenging, while anti-inflammatory effects are observed through protein denaturation inhibition. Furthermore, it demonstrates potential for anti-aging via elastase inhibition and collagen regulation, and for brightening by inhibiting tyrosinase activity.

Research

Clinical Evidence

Medium confidence
Effective range 0.00015–1.5%
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

Effective concentrations for Mirabilis Jalapa Seed Extract vary depending on the target benefit. While some antioxidant effects are observed at very low concentrations (e.g., IC50 at 0.00017124%), benefits for sensitive skin and barrier improvement are noted across a broader range, from 0.00015% up to 1.5%. This wide range suggests that achieving efficacy does not always require extremely high concentrations, and formulation within the lower end of this range can still be impactful for specific claims.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

The pH of Mirabilis Jalapa seed oil has been reported as 6.6. However, specific optimal pH ranges for the stability of the seed extract itself are not available in current research.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Mirabilis Jalapa Seed Extract has not been formally reviewed for safety by major regulatory bodies such as CIR, SCCS, or for FDA GRAS status.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Mirabilis Jalapa Seed Extract is a valuable botanical ingredient, offering comprehensive benefits for sensitive and reactive skin through its soothing, barrier-enhancing, antioxidant, and anti-inflammatory properties, with low irritancy and comedogenicity.

Related

Similar Ingredients

Finding similar ingredients…