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Moumoujus

MIRABILIS JALAPA FLOWER/LEAF/STEM EXTRACT.

Valuable CAS 91722-88-2 / SKIN CONDITIONING

Mirabilis Jalapa Flower/Leaf/Stem Extract is a multi-functional botanical ingredient recognized for its calming and protective actions on sensitive skin. It effectively reduces reactivity, improves skin barrier function, and contributes to collagen synthesis, addressing both discomfort and signs of aging.

Summary

Skin conditioning Skin protecting Anti-inflammatory Collagen boosting Anti-aging Soothing Barrier support Antioxidant Skin brightening Antimicrobial

Science

Mechanism of Action

This extract operates through a multifaceted approach on the skin. It significantly enhances collagen functionality by promoting BMP-1 production from dermal fibroblasts. For sensitive skin, it modulates neuronal pathways by decreasing the overproduction of Nerve Growth Factor (NGF) and TRPV1, molecules implicated in exaggerated responses to stimuli. This action, combined with its ability to thicken the epidermis and reinforce the stratum corneum, results in improved barrier function and reduced reactivity. Furthermore, it exerts calming effects by acting on nerve endings irritated by inflammation, demonstrates antioxidant capacity, inhibits elastase, and up-regulates anti-aging protein expression. It also exhibits inhibitory effects on tyrosinase, suggesting potential for brightening, and possesses antimicrobial properties against various bacteria and fungi.

Research

Clinical Evidence

High confidence
Effective range 0.00015–1.5%
Optimal

The data indicates efficacy for collagen promotion at a low concentration of 0.005%, while sensitive skin benefits are observed across a wider range from 0.00015% to 1.5% (dry residue).

Key findings

  1. 01 Significantly promotes the production of BMP-1 from dermal fibroblasts, thereby enhancing collagen functionality.
  2. 02 Addresses sensitive skin by reducing Nerve Growth Factor (NGF) and TRPV1 overproduction, contributing to epidermal thickening, and strengthening the stratum corneum barrier.
  3. 03 Demonstrated dose-dependent anti-inflammatory effects in animal models, specifically inhibiting paw edema.
  4. 04 Minimum inhibitory concentrations were determined in vitro, indicating antimicrobial potential.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Comprehensive safety assessments from organizations like CIR, SCCS, or FDA for cosmetic application were not available in the provided research.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Mirabilis Jalapa Flower/Leaf/Stem Extract is a valuable botanical ingredient, particularly effective for soothing sensitive and reactive skin, while also offering significant anti-aging benefits through enhanced collagen functionality and antioxidant protection.

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