Science
Mechanism of Action
This extract reduces excessive skin sensitivity by mitigating the overproduction of Nerve Growth Factor (NGF) and activity of the TRPV1 receptor. It strengthens the skin's natural defenses by promoting epidermal thickening and enhancing stratum corneum barrier function. Furthermore, it contributes to anti-aging by upregulating BMP-1, thereby promoting collagen production and inhibiting elastase activity. It also functions as an antioxidant, inhibits tyrosinase for improved tone, and possesses soothing, anti-inflammatory, and antimicrobial properties.
Research
Clinical Evidence
Medium confidence0.005%
Key findings
- 01 At concentrations between 0.00015% and 1.5% (dry residue), the extract effectively prevents and corrects skin hypersensitivity by reducing Nerve Growth Factor (NGF) and TRPV1, concurrently improving epidermal thickness and stratum corneum barrier function.
- 02 A 0.005% concentration (0.05 g/L) was shown to significantly stimulate the production of BMP-1 from dermal fibroblasts, indicating a robust promotion of collagen functionality and visible anti-aging effects.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Stability is a key consideration during formulation. This water-soluble extract can be effectively incorporated using conventional physiologically acceptable solubilizers such as ethanol, propylene glycol, glycerol, butylene glycol, 1,3 propanediol, or polyethylene glycol, or combinations thereof. Emulsifiers may also be utilized to aid solubilization.
Safety
Safety Profile
While the Cosmetic Ingredient Review (CIR) currently notes insufficient data for a full assessment, Mirabilis Jalapa Flower Extract is generally considered safe for use in cosmetic formulations. No specific hazard classifications, pictograms, or precautionary statements have been found under GHS classification according to OSHA HCS.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Mirabilis Jalapa Flower Extract is a valuable, multi-functional ingredient for addressing skin sensitivity and promoting anti-aging effects, demonstrating broad skin compatibility and a low risk profile.
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References
Sources