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Moumoujus

MIRABILIS JALAPA CALLUS CULTURE POWDER.

Insufficient Data CAS 91722-88-2

Mirabilis Jalapa Callus Culture Powder is a plant-derived ingredient sourced from the undifferentiated plant cells (callus) of the 'Four O'Clock' plant. This ingredient is specifically classified for its skin-protecting properties, building on the known benefits of the Mirabilis jalapa plant for enhancing skin comfort and resilience.

Summary

Skin protecting Soothing Barrier support Antioxidant

Science

Mechanism of Action

The proposed mechanism of action, largely extrapolated from general Mirabilis jalapa extracts, includes modulating skin sensitivity by reducing the overproduction of Nerve Growth Factor (NGF) and the activity of the TRPV1 receptor, leading to a soothing effect. It also aims to strengthen the epidermal barrier through promoting the synthesis of occludin, a key protein in tight junctions, and by potentially contributing to epidermal thickening. General Mirabilis jalapa extracts also demonstrate antioxidant effects, inhibition of melanin synthesis, and anti-aging protein expression upregulation. Mirabilis Jalapa Callus Extract is specifically recognized for its skin-protecting attributes.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Mirabilis jalapa flower extract (not callus culture powder) at 0.05 g/L significantly promoted BMP-1 production from dermal fibroblasts, suggesting a potential role in improving collagen functionality.
  2. 02 Mirabilis jalapa extract (not callus culture powder), in concentrations ranging from 0.00015% to 1.5% (as dry residue), has been employed for the non-therapeutic cosmetic treatment of sensitive skin.

Transparency

Dusting Analysis

Not commonly dusted

There is no available data to suggest that this ingredient is commonly dusted or to determine a dusting threshold or red flag percentage.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Specific optimal pH and comprehensive stability data for Mirabilis Jalapa Callus Culture Powder in cosmetic formulations are not explicitly detailed. However, the optimal pH for in vitro callus induction medium for Mirabilis jalapa explants was observed to be approximately 5.7 ± 0.1 or 5.8.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Mirabilis Jalapa Callus Culture Powder has not undergone explicit review by the Cosmetic Ingredient Review (CIR) Expert Panel. Therefore, comprehensive safety assessment data for this specific form is not readily available.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While general Mirabilis jalapa extracts show promise for soothing sensitive skin and supporting barrier function, specific clinical efficacy, safety, and formulation data for the Mirabilis Jalapa Callus Culture Powder itself are currently limited, warranting further dedicated research for precise application guidance.

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