Science
Mechanism of Action
As a surfactant, MIPA-COCOYL SARCOSINATE reduces the surface tension of liquids, enabling the uniform dispersion of oil and water. This facilitates the removal of dirt and excess sebum from skin and hair. It delivers mild cleansing, aids in foam formation, and provides conditioning benefits, contributing to a clean feel without compromising skin barrier integrity.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Clinical irritation and sensitization studies, reviewed by the CIR Expert Panel, indicate that acyl sarcosines, including MIPA-COCOYL SARCOSINATE, are safe for use in rinse-off cosmetic products. For leave-on applications, they are deemed safe at concentrations up to 5%, which represents the highest concentration tested.
- 02 A related sarcosinate, Sodium Lauroyl Sarcosinate, at concentrations between 2-5%, was found to be non-irritating and non-sensitizing. It also demonstrated the ability to reduce moisture loss from the skin by forming a protective, hydrophobic layer.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
While specific optimal pH data for MIPA-COCOYL SARCOSINATE is not available, related sarcosinates demonstrate good stability across various pH ranges. Sodium Cocoyl Sarcosinate is stable between pH 6-8, and Sodium Lauroyl Sarcosinate maintains stability from pH 5.5 to alkaline conditions.
Conflicts
- Must not be used in formulations where the formation of N-nitroso compounds is possible, as sarcosine can form N-nitrososarcosine, a known animal carcinogen.
- This ingredient may enhance the penetration of other substances through the skin. Therefore, caution is advised when formulating with ingredients whose safety is contingent on minimal dermal absorption or where enhanced absorption poses a concern.
Safety
Safety Profile
MIPA-COCOYL SARCOSINATE is considered safe for use in rinse-off products and in leave-on products at concentrations up to 5%. It is imperative to avoid formulations that could lead to the formation of N-nitroso compounds. Data regarding the safety of this ingredient when inhaled is insufficient. Furthermore, products incorporating MIPA-COCOYL SARCOSINATE must be meticulously formulated to ensure they are non-irritating.
Your Skin
Skin Compatibility
Our Assessment
Verdict
MIPA-COCOYL SARCOSINATE is a valuable, mild surfactant offering effective cleansing and conditioning benefits suitable for all skin types, with low irritancy and comedogenicity, provided strict adherence to formulation safety guidelines is maintained.
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