MILK PROTEIN EXTRACT.

Key findings

1. 01 While precise concentration-specific clinical trials for 'Milk Protein Extract' are limited, milk proteins generally are utilized in dermatology for wound healing, tissue regeneration, and treating conditions like acne vulgaris and plaque psoriasis. They are observed to reduce acne lesions, regulate sebum, ameliorate inflammation, and provide moisturizing, protective, toning, smoothing, anti-irritation, whitening, soothing, and anti-aging effects. Bioactive peptides derived from milk proteins have demonstrated antioxidant and antimicrobial activity.

Stability

The stability and susceptibility of milk proteins to denaturation and aggregation are highly dependent on factors such as heating temperature, duration, mechanical shear forces, pH, and the concentration of proteins and minerals. Changes in pH notably influence the electrostatic interactions between protein molecules, impacting the structural integrity of casein micelles. For instance, milk protein concentrate suspensions showed fragmentation of protein aggregates at pH 6.8 and increased heat-induced micellar dissociation at pH 7.5 under shear conditions. Solubility can also be affected by interactions with compounds like polyphenols.

Conflicts

• Calcium (in the absence of a surfactant, adding calcium to an aqueous solution of casein can lead to precipitation).
• Factors leading to insolubility in milk protein concentrates include casein-casein and casein-whey protein interactions, formation of casein crosslinks in the presence of calcium ions, and lactose-protein interactions (Maillard reaction), especially during manufacturing and storage.