MICROCOCCUS LYSATE FILTRATE.

This ingredient, derived from marine sources or Micrococcus luteus, contains Baringolin, a cyclothiopeptide, which confers strong antibacterial properties against Gram-positive bacteria and inhibits Gram-negative strains, alongside potent anti-inflammatory effects. It notably possesses DNA repair capabilities, acting as an endonuclease that identifies and remedies UV-induced DNA damage by stimulating the excision repair process. This process creates precise microdamage necessary for polymerase activity, thereby intensifying the skin's intrinsic self-repair mechanisms. A metabolomics analysis further indicates a rich composition of amino sugars, carbohydrates, lipids, oxyaromatic compounds, phytochemicals (flavonoids), and peptides, which collectively contribute to its regenerative, antioxidant, and structural benefits. It actively promotes skin regeneration by increasing cell migration, enhancing the expression of skin moisturizing-related hyaluronic acid synthase 3 (HAS3) or aquaporin 3 (AQP3), and inhibiting inflammatory cytokines (e.g., IL-1β) or itch-related factors (e.g., TSLP).