Science
Mechanism of Action
This ingredient functions through several key pathways. It contains Baringolin, a cyclothiopeptide, providing potent antibacterial action against Gram-positive and Gram-negative bacteria, including antibiotic-resistant strains, thereby addressing blemish-causing microbes. As a DNA repair enzyme (endonuclease from Micrococcus luteus), it actively recognizes and excises UV-induced pyrimidine dimers from damaged DNA, facilitating natural repair processes. Furthermore, it stimulates skin regeneration by enhancing cell migration, increases the expression of critical moisturizing factors like hyaluronic acid synthase 3 (HAS3) and aquaporin 3 (AQP3), and mitigates inflammation by inhibiting cytokines such as IL-1β and reducing itch-related factors like TSLP. Its rich composition of amino sugars, carbohydrates, lipids, oxyaromatic compounds, flavonoids, and peptides contributes to its comprehensive regenerative, antioxidant, and structural support properties.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Demonstrated a 27% reduction in visible blemishes for individuals with acne types I and II.
- 02 Topical application resulted in an 18% reduction of pyrimidine dimers in UV-damaged skin.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Optimal stability is maintained at room temperature (23-30°C), avoiding extreme heat or cold. Should appearance change due to temperature, gentle warming to 45-50°C with mixing can restore consistency. It must be incorporated into the water phase at temperatures below 45°C. To prevent oxidation and contamination, protect from UV light using opaque or amber containers and minimize air exposure with airtight seals.
Conflicts
- strong acids
- strong bases
- oxidizing agents
Safety
Safety Profile
Described as a natural, safe, and effective ingredient without reported side effects. It carries a 'LOW HAZARD' rating by EWG and is certified by SkinSAFE as Irritant Free, Dye Free, and devoid of common allergens including preservatives, fragrances, parabens, lanolin, MCI/MI, nickel, gluten, soy, propylene glycol, balsam of peru, and oils.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Micrococcus Lysate is a valuable ingredient, demonstrating clinical efficacy in reducing blemishes and repairing UV-induced DNA damage, coupled with strong anti-inflammatory, antibacterial, and regenerative properties, making it highly beneficial for diverse skin concerns.
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