Science
Mechanism of Action
This extract operates by precisely targeting the skin's natural capacity to synthesize hyaluronic acid (HA). It notably increases the expression of hyaluronan synthase (HAS2), a pivotal enzyme responsible for HA synthesis, thereby reactivating natural hydration mechanisms that typically diminish with age. The augmented HA levels lead to enhanced skin moisture retention and a refined skin texture.
Research
Clinical Evidence
Medium confidence2%
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The active ingredient derived from Metschnikowia agaves yeast exhibits stability within a pH range of 4.3 to 5.5, indicating its suitability for integration into various cream formulations.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has issued an 'Insufficient Data Announcement' for Metschnikowia Agaves Extract. They have specifically requested additional data, including confirmatory dermal sensitization information and details regarding its food use or Generally Recognized As Safe (GRAS) status, to complete its safety assessment.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While exhibiting promising clinical efficacy in boosting hyaluronic acid and improving skin texture, further safety data is currently required by the CIR for a comprehensive assessment.
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References
Sources