Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

METHYLTHIOPROPYLAMIDO ACETYL METHIONINE.

Valuable CAS 1258540-06-5 / SKIN PROTECTING

METHYLTHIOPROPYLAMIDO ACETYL METHIONINE, known by its trade name Methiopeptide®, is an advanced methionine derivative designed to protect and energize skin cells. It acts as a potent antioxidant, safeguarding against oxidative stress and supporting cellular regeneration for optimal skin health.

Summary

Antioxidant Skin Energizing Skin Protecting Photoprotection Cell Regeneration Support

Science

Mechanism of Action

This complex molecule, derived from methionine and acetylmethionine, functions primarily as a skin energizer and antioxidant. It effectively protects cellular mitochondria from oxidative stress, thereby ensuring consistent ATP production and maintaining vital energy supply for the skin. Furthermore, it offers robust protection against damaging free radicals, supports DNA integrity, and provides photoprotective benefits. Its unique structure allows it to be recognized and regenerated by the skin's Methionine Sulfoxide Reductase (MSR) enzyme, facilitating enhanced bioavailability and sustained defense against reactive oxygen species (ROS).

Research

Clinical Evidence

Medium confidence
Effective range 0.5–2%
Optimal

N/A

Key findings

  1. 01 Demonstrated capability to shield cell respiration from the impacts of aging and harmful oxidative stress.
  2. 02 Shown to protect mitochondrial function from oxidative stress, thereby supporting the skin's essential energy supply.
  3. 03 Successfully maintained optimal energy levels even under H2O2-induced oxidative stress, highlighting its robust protective qualities.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The ingredient's structural characteristics are engineered to resist degradation within the superficial skin layers, ensuring long-lasting protective effects. The raw material is typically supplied as a preservative-free 15% hydroglycolic solution.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While the Cosmetic Ingredient Review (CIR) has not specifically assessed METHYLTHIOPROPYLAMIDO ACETYL METHIONINE, general safety evaluations indicate a favorable profile. EWG assigns a low harm score of 3, indicating minimal concerns for cancer, allergies, immunotoxicity, and developmental or reproductive toxicity. SkinSAFE categorizes it as 'Irritant Free' and generally free from common allergens. Acetyl methionine, a closely related compound, is broadly considered safe for both cosmetic and food applications, further supporting its benign nature.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

METHYLTHIOPROPYLAMIDO ACETYL METHIONINE is a valuable ingredient for advanced skincare, offering multifaceted protection against oxidative stress and enhancing cellular energy, suitable for all skin types with a low risk of irritation.

Related

Similar Ingredients

Finding similar ingredients…