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Moumoujus

METHYLHEPTYLGLYCERIN.

Valuable CAS 182015-50-5 / DEODORANT, HUMECTANT, SKIN CONDITIONING - MISCELLANEOUS

Methylheptylglycerin is a precision skincare ingredient recognized for its multi-functional benefits, including potent deodorant action, humectant properties, and skin conditioning. It effectively targets odor-causing bacteria while supporting skin hydration and overall skin health.

Summary

Deodorant Humectant Skin Conditioning

Science

Mechanism of Action

This medium-chain amphiphilic compound exerts its action by selectively inhibiting the growth of key bacteria, such as *Corynebacterium xerosis* and *Staphylococcus aureus*, which are primary contributors to body odor. It interacts with bacterial cell membranes, enhancing their permeability and ultimately leading to cellular collapse, all while maintaining the integrity of the skin's natural microbiome. Additionally, Methylheptylglycerin acts as a humectant, attracting and retaining moisture, and provides beneficial skin conditioning effects.

Research

Clinical Evidence

High confidence
Effective range 0.5–1.5%
Optimal

0.5-1.5%

Key findings

  1. 01 Achieved Minimum Inhibitory Concentration (MIC) against *Staphylococcus aureus*.
  2. 02 Achieved Minimum Inhibitory Concentration (MIC) against *Staphylococcus epidermidis*.
  3. 03 Demonstrated significant inhibition of *Corynebacterium xerosis*, a key contributor to malodor, within 30 seconds during Time Kill studies.
  4. 04 Recommended use level for preservation in Oil-in-Water (O/W) Emulsions.
  5. 05 Recommended use level for preservation in O/W Sunscreens, Cleansers, and Wipe Juices.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Methylheptylglycerin can be incorporated into the water phase at temperatures below 80°C or added during the cool-down phase at approximately 40°C. For formulations requiring a clear final product, a solubilizer may be necessary.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

EWG Skin Deep assigns Methylheptylglycerin 'Low' concern for both Cancer and Allergies & Immunotoxicity. SkinSAFE indicates it is generally safe for teens, lips, babies, and eyelids, and is free from common allergy-causing preservatives and fragrances. While considered 'Generally non-irritating' by Paula's Choice, the likelihood of irritation may increase when combined with other problematic ingredients.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Methylheptylglycerin is a valuable multifunctional ingredient, offering effective odor control and antimicrobial benefits alongside humectant and skin conditioning properties, making it suitable for a wide range of precision skincare applications across all skin types.

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