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METHYLGLUCOSE DIOLEATE/HYDROXYSTEARATE.

Valuable CAS 224580-86-3 / SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

Methylglucose Dioleate/Hydroxystearate is a versatile non-ionic ingredient that functions as an emulsifier, thickener, and surfactant in advanced skincare formulations. It contributes significantly to product stability while also enhancing the skin's natural moisture retention.

Summary

Emulsifying Viscosity Controlling Skin Conditioning Surfactant Humectant

Science

Mechanism of Action

On the skin, Methylglucose Dioleate/Hydroxystearate forms a delicate, protective film that effectively reduces moisture loss and substantially increases water retention, resulting in a noticeably softer and healthier skin feel. As a surfactant, it expertly blends oil and water components, facilitating the gentle removal of dirt and oils during cleansing. Furthermore, it stabilizes formulations by preventing phase separation and possesses the notable ability to reduce the overall irritation potential of complex cosmetic systems.

Research

Clinical Evidence

High confidence
Effective range 0.5–5%
Optimal

5%

Key findings

  1. 01 Typical applications demonstrate its effectiveness as a surfactant, emulsifier, and thickener at concentrations between 0.5% and 3%, providing stability and improving skin hydration.
  2. 02 Its role as a thickener is well-established, with recommended usage levels extending up to 5.0% across diverse product types.
  3. 03 Despite an in vitro assay classifying it as a slight irritant at 1,125.56 µg/ml, a comprehensive Draize test at a 100% concentration showed no ocular irritation in vivo, indicating a robust safety profile.

Transparency

Dusting Analysis

Not commonly dusted

No available research data suggests that Methylglucose Dioleate/Hydroxystearate is associated with 'dusting' or has specific concentration thresholds that would trigger such concerns.

The Formula

Formulation

Solubility
Both
Optimal pH 4 – 9
0 7 14

Stability

This non-ionic thickener exhibits broad compatibility with both anionic and amphoteric surfactant systems. It is robustly salt tolerant and maintains stability in acidic environments. Its formulation versatility allows for easy incorporation, including cold processing, without requiring heating or pH adjustments, and it does not compromise the foam volume or texture of surfactant-based formulations.

Synergies

  • Demonstrates excellent compatibility with a wide range of anionic and amphoteric surfactant systems.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
5%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that Methylglucose Dioleate/Hydroxystearate, within its class of methyl glucose polyethers and esters, is safe for use in cosmetic applications at concentrations up to 5%. While an in vitro assay indicated a slight irritant response at 1,125.56 µg/ml, in vivo studies using 100% concentration did not induce ocular irritation. It is considered a non-irritant and can actively reduce the irritation potential of formulated products, though it is advised not to use on broken skin.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Methylglucose Dioleate/Hydroxystearate is a valuable ingredient due to its multifaceted benefits in stabilizing formulations, enhancing texture, and providing significant skin conditioning and moisture retention, all supported by a favorable safety profile.

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