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METHYLCYCLOPENTADECENONE.

Questionable CAS 82356-51-2 / FRAGRANCE

Methylcyclopentadecenone is a synthetic fragrance compound primarily valued for its potent and elegant musk aroma in cosmetic and personal care products. It also functions as a masking agent to neutralize undesirable odors in formulations.

Masking Fragrance

Science

This ingredient functions by imparting a distinct musk fragrance to products, thereby enhancing their olfactive profile or perfuming the skin. Its masking properties allow it to reduce or inhibit unwanted odors. No specific mechanism of action demonstrating direct benefits to skin health or function, beyond its aromatic contribution, has been identified in current research.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Methylcyclopentadecenone is incorporated for its specific fragrance properties rather than as a 'dusting' ingredient added without clear functional intent for direct skincare benefits.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

While no specific optimal pH range is documented, as a macrocyclic ketone, Methylcyclopentadecenone is generally expected to exhibit good stability. It demonstrates excellent substantivity on various substrates including skin, hair, and fabric.


Safety

CIR Status
Not reviewed
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Expert Panel has not conducted a safety assessment, nor has the Scientific Committee on Consumer Safety (SCCS) published an opinion specifically on Methylcyclopentadecenone. While the FDA does not require pre-market approval for cosmetic ingredients (excluding color additives), products containing harmful substances are prohibited. It is listed as 'Restricted' by EWG and flagged with 'MODERATE' concern for allergies & immunotoxicity, indicating a possible human skin toxicant or allergen.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Questionable

Primarily a fragrance and masking agent, Methylcyclopentadecenone lacks identified direct skincare benefits and presents a moderate risk of sensitization, making its inclusion in precision skincare products questionable.


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