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METHYL-PHENYLBUTANOL.

Questionable CAS 705-58-8 / PERFUMING

METHYL-PHENYLBUTANOL is a synthetic aromatic alcohol valued for its versatile fragrance profile. It contributes a range of scents, including floral, green, fruity, lily-like, or rosy notes, designed to enhance the sensory appeal of a product or to provide direct skin perfuming.

fragrance

Science

METHYL-PHENYLBUTANOL functions by activating olfactory receptors to impart a specific aroma, thereby enhancing the product's scent or leaving a pleasant fragrance on the skin. Its action is purely sensory, without known bioactive effects on skin physiology.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

METHYL-PHENYLBUTANOL demonstrates general stability under typical formulation conditions.

Conflicts

  • strong oxidizing agents

Safety

CIR Status
Not reviewed
Sensitization risk Moderate

While METHYL-PHENYLBUTANOL lacks a dedicated Cosmetic Ingredient Review (CIR) assessment, safety data for its common isomer, 2-methyl-4-phenyl-2-butanol (CAS 103-05-9), indicates it is non-genotoxic. However, skin sensitization potential for the isomer presents mixed results, with a human cell line activation test showing a positive response, although other in vitro and in vivo assays were negative or inconclusive. The Globally Harmonized System (GHS) classifies the isomer with a warning for serious eye irritation (H319). It is recognized by the FDA as a flavoring agent or adjuvant.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Questionable

Given its exclusive role as a fragrance agent with no direct skincare benefits and a moderate irritancy potential identified for its isomer, METHYL-PHENYLBUTANOL's utility in precision skincare is considered questionable.


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