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METHYL DIHYDROXY-DIMETHYLBENZOATE.

Questionable CAS 4707-47-5 / PERFUMING

Methyl Dihydroxy-Dimethylbenzoate functions primarily as a fragrance ingredient, imbuing products and skin with a distinct powdery and woody-sweet aroma, including notes of oak and treemoss. While enhancing sensory appeal, this compound carries a notable potential for skin irritation and sensitization, necessitating cautious formulation in precision skincare.

Fragrance

Science

This ingredient's primary mechanism is to serve as a fragrance, enhancing the olfactive profile of a cosmetic product. It functions as an excellent fixative, which helps to stabilize and prolong the longevity of a scent, providing a specific aromatic character described as powdery, woody-sweet, with nuances of oak and treemoss.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

No specific data regarding 'dusting' behavior for this ingredient has been identified.


The Formula

Solubility
Unknown
Optimal pH 1 – 9
0 7 14

Stability

The material demonstrates stability across a broad pH range from 1 to 9 and exhibits moderate alkali stability. Optimal storage conditions involve a cool, dry, and well-ventilated environment under an inert gas, with the container kept tightly closed due to its hygroscopic nature.


Safety

CIR Status
Not reviewed
Sensitization risk Moderate

EWG has indicated 'SOME' concern regarding potential skin allergies and irritation. An in vitro skin sensitization study (KeratinoSens assay) reported an EC1.5 value of 151.97 µM, suggesting a potential for sensitization. Furthermore, the Material Safety Data Sheet (MSDS) explicitly states 'H315: Causes skin irritation', noting that concentrated forms may lead to mild skin irritation. This substance is not suspected to be an environmental toxin, and components are not identified as probable human carcinogens by IARC at levels ≥ 0.1%. However, data on developmental & reproductive toxicity or overall cancer risk is currently unavailable.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Questionable

Primarily a fragrance ingredient with no direct skincare benefits, Methyl Dihydroxy-Dimethylbenzoate's documented potential for skin irritation and sensitization renders its inclusion in precision skincare formulations questionable.


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