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METHYL CAPROOYL TYROSINATE.

Valuable CAS 1104874-94-3 / SKIN PROTECTING

Methyl Caprooyl Tyrosinate, also recognized as Defensamide, is a sophisticated peptide engineered to enhance the skin's innate defense mechanisms. It functions by stimulating the endogenous production of crucial antimicrobial peptides, thereby fortifying the skin barrier against environmental stressors and microbial challenges.

Skin Protecting Antimicrobial Support Skin Barrier Fortification

Science

This active ingredient operates by significantly boosting the skin's natural generation of antimicrobial peptides (AMPs), specifically cathelicidin antimicrobial peptide (CAMP). Its precise mechanism involves potentiating Sphingosine Kinase 1 (SPHK1) activity, which leads to an elevation in cellular Sphingosine-1-phosphate (S1P) levels. This cascade subsequently activates the transcription factor NF-κB, a key regulator in inducing CAMP production. By enhancing CAMP expression, Methyl Caprooyl Tyrosinate strengthens the skin's intrinsic defense system and can help suppress the proliferation of bacteria such as Staphylococcus on the skin's surface, notably without promoting antibiotic resistance.


Research

Medium confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Methyl Caprooyl Tyrosinate has not undergone a specific safety assessment by the Cosmetic Ingredient Review (CIR) or the Scientific Committee on Consumer Safety (SCCS).


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Methyl Caprooyl Tyrosinate presents a valuable mechanism for boosting the skin's natural antimicrobial defenses, contributing to a more resilient and protected skin barrier.


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