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METHYL BENZODIOXEPINONE.

Optional CAS 28940-11-6 / FRAGRANCE, PERFUMING

Methyl Benzodioxepinone is a synthetic fragrance ingredient recognized for imparting a distinct fresh, watery, clean, melon, green, marine, and ozone-like aroma. It is incorporated into skincare and cosmetic products primarily to enhance their olfactive appeal and perfume the skin.

Fragrance

Science

This ingredient functions by releasing volatile molecules that stimulate olfactory receptors, thereby creating a desired scent profile in cosmetic formulations and on the skin.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH 2 – 8.5
0 7 14

Stability

Methyl Benzodioxepinone exhibits robust stability across a pH range of 2.0 to 8.5, maintaining over 90% integrity for at least 5 days at 40°C. Notably, it also demonstrates resilience in challenging formulations containing strong reducing or oxidizing agents, such as detergents, bleaching products, and aluminum salt-based antiperspirants, where other aldehydes might degrade.


Safety

CIR Status
Not reviewed
Sensitization risk Low

A comprehensive safety assessment by the Research Institute for Fragrance Materials (RIFM) indicates Methyl Benzodioxepinone is not genotoxic. It demonstrates a calculated Margin of Exposure (MOE) exceeding 100 for repeated dose and reproductive toxicity. The No Expected Sensitization Induction Level (NESIL) for skin sensitization is established at 1100 μg/cm², with no reported photoirritating or photoallergenic potential. Although not formally reviewed by CIR, the RIFM assessment is consistent with IFRA industry safety standards, and current usage volumes are below risk quotients in major markets. The ingredient is also listed in FDA GSRS and UNII databases.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

Methyl Benzodioxepinone is a stable, low-irritancy fragrance component, well-suited for adding a fresh, aquatic aroma to a wide range of skincare and cosmetic products.


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