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METHYL 2,4-DIHYDROXYBENZOATE.

Insufficient Data CAS 2150-47-2 / SKIN CONDITIONING

Methyl 2,4-dihydroxybenzoate is a versatile ingredient offering enhanced sun protection by absorbing UVB and some UVA radiation. It provides antioxidant benefits, aiding in the reduction of wrinkles and delaying skin aging, while also acting as a skin-conditioning agent and preservative. Additionally, it exhibits anti-inflammatory effects, making it suitable for diverse skincare applications.

skin conditioning antioxidant uv absorber preservative anti-inflammatory

Science

This compound primarily functions by absorbing ultraviolet radiation, specifically in the UVB and certain UVA spectrums, thereby augmenting sun protection. Its antioxidant activity is attributed to its polyphenolic structure, which helps neutralize free radicals, mitigating oxidative stress and supporting anti-aging processes. Additionally, it serves as a precursor in the synthesis of flavonoids and other polyphenolic compounds known for their potent antioxidant effects. Its anti-inflammatory action is observed in cleansing product applications.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

For laboratory applications, Methyl 2,4-dihydroxybenzoate demonstrates solubility in DMSO at a concentration of 30 mg/mL (178.41 mM), with sonication recommended for optimal dissolution. Stock solutions should be stored at -80°C for up to 6 months or at -20°C for 1 month under a nitrogen atmosphere to maintain stability.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Methyl 2,4-dihydroxybenzoate carries FDA UNII XE68BU3OYJ. Sigma-Aldrich safety data indicates hazard codes H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation), suggesting a potential for irritation. It is classified as WGK 3, denoting high hazard to water. There are no specific CIR or SCCS safety assessments available for this exact compound; assessments for similar, isomeric compounds like Methyl Salicylate and Methylparaben exist but are not directly applicable.


Your Skin

No Normal
No Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Insufficient Data

While offering promising benefits as a UV absorber, antioxidant, and anti-inflammatory agent, the lack of specific clinical studies, official safety assessments by CIR/SCCS, and noted irritation potential necessitates further research for comprehensive evaluation in cosmetic applications.


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