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METHOXY PEG-100.

Valuable CAS 9004-74-4 / HUMECTANT, SOLVENT

METHOXY PEG-100 is a water-soluble linear polymer, a specific type of Methoxy Polyethylene Glycol (mPEG). It functions primarily as a solubilizer and an absorption enhancer, facilitating the integration and delivery of other ingredients within cosmetic formulations.

Summary

Solubilizer Absorption Enhancer Surfactant Emulsifier Cleansing Agent Humectant Skin Conditioner

Science

Mechanism of Action

As a hydrophilic polymer, METHOXY PEG-100 operates by enhancing the miscibility of poorly soluble compounds, ensuring their uniform dispersion throughout a product. Its key mechanism involves improving the skin's capacity to absorb various additives, thereby potentially increasing the bioavailability of active ingredients. Additionally, it contributes to formulation stability and aesthetics by acting as a surfactant, emulsifier, cleansing agent, humectant, and skin conditioner.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Methoxy polyethylene glycol demonstrates robust chemical stability, resisting degradation by hydrolysis. It is compatible with a wide array of solvents and chemicals, ensuring consistent performance within diverse formulations.

Synergies

  • Enhances the absorption and bioavailability of other cosmetic additives.

Safety

Safety Profile

CIR Status
Safe with restrictions
Sensitization risk Unknown

While related Polyethylene Glycols (PEGs) with molecular weights over 6,000 are permitted as food additives by the FDA, the cosmetic use of METHOXY PEG-100 carries specific restrictions. The Cosmetic Ingredient Review (CIR) Expert Panel has assessed PEG Stearates as safe, but for METHOXY PEG-100 (an ether), EWG notes restrictions related to concentration, potential impurities (ethylene oxide, 1,4-dioxane), product types, or manufacturing methods. Adherence to these guidelines is crucial for safe use.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

METHOXY PEG-100 is a valuable excipient that significantly improves ingredient solubilization and skin absorption, provided its integration strictly adheres to established safety restrictions and purity standards.

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