Science
Mechanism of Action
This complex fusion peptide operates via a dual mechanism. Its SH-Polypeptide-9 component functions as a Vascular Endothelial Growth Factor (VEGF), a cell signaling protein crucial for stimulating blood vessel formation. This action supplies essential nutrients to fibroblast cells, promoting their growth and migration, which in turn aids in collagen production, wound healing, and improved skin elasticity. The Decapeptide-40 component complements this by stimulating the skin's intrinsic protein synthesis, including collagen, delivering crucial conditioning and protective benefits. Engineered for enhanced skin permeation, the ingredient delivers these physiologically active substances efficiently into the deep dermal layers, targeting overall skin regeneration and wrinkle improvement.
Research
Clinical Evidence
Medium confidence0.1%
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The Sh-polypeptide 9 component benefits from double-layered capsulation technology, which is known to enhance its skin penetration, stability, and purity within formulations.
Safety
Safety Profile
The full ingredient, METHIONYL SH-POLYPEPTIDE-9 DECAPEPTIDE-40, has not yet been specifically reviewed by regulatory bodies such as CIR, SCCS, or FDA. However, its component SH-POLYPEPTIDE-9 is not listed on EWG's Skin Deep Restricted or Unacceptable Lists. Safety has been confirmed in clinical trials for related decapeptide ingredients used in vitiligo treatment, indicating a favorable safety profile.
Your Skin
Skin Compatibility
Our Assessment
Verdict
METHIONYL SH-POLYPEPTIDE-9 DECAPEPTIDE-40 is a valuable active peptide, demonstrating strong potential in skin regeneration, anti-aging, and barrier support based on its mechanistic actions and clinical data on its components.
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