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METHIONYL SH-OLIGOPEPTIDE-2 DECAPEPTIDE-40.

Valuable / ANTIOXIDANT

METHIONYL SH-OLIGOPEPTIDE-2 DECAPEPTIDE-40 is a synthetic signaling peptide designed to activate the skin's intrinsic repair mechanisms. It delivers multi-functional benefits, including potent antioxidant defense, comprehensive skin conditioning, and enhanced environmental protection. This ingredient works to improve overall skin health, appearance, and resilience.

Summary

Antioxidant Skin-conditioning Hair-conditioning Signaling Skin regeneration Skin barrier support Wrinkle reduction

Science

Mechanism of Action

This synthetic peptide operates as a crucial signaling molecule, precisely activating the skin's inherent repair pathways. It diligently stimulates the regeneration of mature skin cells, thereby reinforcing the skin's structural integrity and contributing to a visible reduction in the appearance of wrinkles. Functioning as an antioxidant, it actively inhibits oxygen-promoted reactions, effectively preventing the oxidation and subsequent deterioration of other ingredients within a formulation. Moreover, it offers significant skin conditioning properties, promoting a softer, smoother, and more hydrated skin feel while improving its overall appearance. Additionally, it bolsters skin protection by forming a robust barrier against diverse environmental stressors such as pollution and UV radiation, thus maintaining skin integrity and resilience.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While METHIONYL SH-OLIGOPEPTIDE-2 DECAPEPTIDE-40 itself does not have a specific CIR (Cosmetic Ingredient Review) or SCCS (Scientific Committee on Consumer Safety) status, its component, SH-Oligopeptide-2, is recognized as safe for cosmetic use by regulatory authorities like the European Cosmetics Directive. Side effects and adverse reactions for closely related ingredients (e.g., R-(Sh-Polypeptide-2 Decapeptide-40)) are generally reported as uncommon, though guidelines recommend caution and patch testing for potential allergies. The ingredient is produced synthetically via E. coli fermentation, ensuring high purity.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

METHIONYL SH-OLIGOPEPTIDE-2 DECAPEPTIDE-40 is a valuable, multi-functional peptide that supports skin regeneration, provides antioxidant defense, conditions, and protects against environmental stressors, despite the current absence of specific quantitative clinical efficacy data.

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