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Moumoujus

METHIONYL RH-POLYPEPTIDE-125.

Insufficient Data / HAIR CONDITIONING

Methionyl RH-Polypeptide-125 is a peptide designed to signal the skin's inherent repair mechanisms, promoting regeneration and structural reinforcement. The methionine component of this polypeptide further contributes potent antioxidant properties.

Summary

Antioxidant Skin-restoring ingredient

Science

Mechanism of Action

This polypeptide functions by generally signaling the skin to activate its endogenous repair mechanisms, characteristic of peptides in anti-aging applications. It aims to stimulate the regeneration of mature skin, strengthen its underlying structure, and contribute to a visible reduction in the appearance of wrinkles while enhancing skin elasticity. The methionine residue within the polypeptide additionally acts as a powerful antioxidant.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

Due to the absence of specific clinical studies detailing effective concentrations or skin benefits, it is not possible to determine if this ingredient is commonly 'dusted' at ineffective percentages.

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 6
0 7 14

Stability

Peptides in solution are less stable than their lyophilized (freeze-dried) counterparts. Optimal stability for solutions containing this polypeptide is typically achieved within a pH range of 5 to 6. To preserve integrity, it is recommended to prepare single-use aliquots and store them at very low temperatures (-20°C or -80°C) to prevent degradation from repeated freeze-thaw cycles. As a polypeptide, its conformation and stability are known to be sensitive to pH variations.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

There is no specific safety assessment from major regulatory bodies such as the Cosmetic Ingredient Review (CIR), the Scientific Committee on Consumer Safety (SCCS), or the FDA directly for METHIONYL RH-POLYPEPTIDE-125. General information regarding unrated ingredients on some platforms suggests a potential for irritation, though this is not specifically attributed to this particular polypeptide.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While aligning with general peptide benefits for skin repair and providing antioxidant action, specific clinical efficacy data, safety assessments, and optimal usage parameters for METHIONYL RH-POLYPEPTIDE-125 are currently insufficient for a definitive recommendation in skincare formulations.

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