Science
Mechanism of Action
This extract primarily functions by providing significant antioxidant defense, mitigating cellular damage through the inhibition of hydrogen peroxide-induced lipid peroxidation and a substantial reduction in intracellular reactive oxygen species (ROS) accumulation. Its efficacy is attributed to a complex profile of beneficial compounds including rutin, quercetin, myricetin, and gallic acid. Beyond its antioxidant capacity, it supports skin integrity with notable anti-inflammatory, antibacterial, and antifungal actions.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 At a concentration of 1.0 mg/mL, lyophilized Metasequoia Glyptostroboides Leaf Extract inhibited hydrogen peroxide-induced lipid peroxidation and reduced intracellular ROS in neuronal PC12 cells. This antioxidant activity was comparable to or superior to ascorbic acid.
- 02 Oral administration ranging from 0.125 mg/mL to 2.0 mg/mL over 15 days demonstrated neuroprotective effects in male Balb/c mice, indicating systemic biological activity, although this was not a direct topical skin application study.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
Formal safety assessments by major regulatory bodies such as CIR, SCCS, or FDA for topical application were not identified in the provided research data.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While displaying robust in vitro antioxidant and diverse protective properties, the absence of direct topical human efficacy and safety data renders its comprehensive precision skincare potential currently underexplored.
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References
Sources