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Moumoujus

MESUA FERREA BARK/LEAF OIL.

Optional / HAIR CONDITIONING

Mesua Ferrea Bark/Leaf Oil is a botanical extract recognized for its broad spectrum of benefits, including significant antioxidant, anti-inflammatory, and antimicrobial properties. Traditionally utilized for skin healing and soothing, this oil offers a multifaceted approach to skin health, targeting irritation and promoting a balanced complexion.

Summary

Antioxidant Anti-inflammatory Antimicrobial Antibacterial Antifungal Skin Soothing Wound Healing Antiseptic Hair Conditioning

Science

Mechanism of Action

This oil acts on the skin through its rich profile of phytochemicals, such as phenyl coumarins, xanthones, triterpenoids, fats, and flavonoids. These compounds collectively contribute to its antioxidant capacity, protecting skin from oxidative stress, and exert anti-inflammatory effects by inhibiting pathways like 5-LOX. Furthermore, its antimicrobial action helps in combating specific bacteria and fungi, supporting overall skin hygiene and recovery.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Leaf essential oil demonstrated antibacterial activity against Staphylococcus aureus at 125 mg/mL.
  2. 02 Leaf essential oil showed antibacterial effects against E. coli at 250 mg/mL.
  3. 03 Leaf essential oil exhibited antioxidant capacity, achieving 50% inhibition (IC50) of DPPH radicals at 31.67 mg/mL.
  4. 04 An ethyl acetate bark extract demonstrated 76.58% inhibition of 5-LOX activity at 100 µg/mL (IC50 46.65 µg/mL), indicating anti-inflammatory potential.
  5. 05 An ethyl acetate bark extract provided a 77.13% protective effect on HRBC membrane stabilization at 500 µg/mL, suggesting anti-inflammatory properties.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

As an oil, Mesua Ferrea Bark/Leaf Oil is inherently oil-soluble. While no specific optimal pH range for the oil's stability was found, a nanoemulsion of its leaf extract has demonstrated stability around a pH of 6.2 ± 0.15.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

There is currently no specific regulatory safety assessment by CIR, SCCS, or FDA for Mesua Ferrea Bark/Leaf Oil. It is recognized and listed as a cosmetic ingredient in COSMILE Europe. A study on Mesua ferrea seed oil suggested cellular safety, but this does not directly pertain to the regulatory safety of the bark/leaf oil.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Optional

With compelling in-vitro evidence for its antioxidant, anti-inflammatory, and antimicrobial actions, Mesua Ferrea Bark/Leaf Oil presents as a versatile ingredient, though further human clinical data would refine its precise dermatological applications.

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