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MEROXAPOL 254.

Essential CAS 9003-11-6 / CLEANSING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

Meroxapol 254 is a non-ionic surfactant and a type of poloxamer, primarily valued for its ability to reduce surface tension on the skin. This property makes it an effective cleansing agent, facilitating the removal of dirt and oils, and a crucial emulsifier in cosmetic formulations. It belongs to a versatile class of compounds recognized for broader tissue support potential.

Summary

Emulsifying Surfactant Cleansing

Science

Mechanism of Action

Meroxapol 254 operates as a non-ionic surfactant by significantly lowering the surface tension of liquids on the skin. This action facilitates the emulsification of oil and water, enabling the effective removal of dirt, sebum, and other impurities. Furthermore, as a poloxamer, it may contribute to skin integrity through mechanisms such as wound cleansing, inhibiting protein aggregation, potentially aiding cellular membrane repair, and stabilizing antimicrobial agents.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

As a block copolymer, Meroxapol 254, like other poloxamers, exhibits robust stability across a wide pH spectrum, ensuring consistent performance in various formulations.

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

Meroxapol 254 is recognized in the EU Cosmetic Ingredient Inventory for its functional roles. Comprehensive safety assessments by the CIR Expert Panel on various poloxamers, including similar grades, have consistently demonstrated a lack of dermal irritation or sensitization in animal models and human clinical tests. Manufacturers are advised to uphold rigorous purification standards to ensure minimal levels of residual ethylene oxide, propylene oxide, and 1,4-dioxane, confirming its safety for cosmetic applications.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Essential

Meroxapol 254 is an essential non-ionic surfactant and emulsifier, offering versatile cleansing properties and broad skin compatibility with a low risk of irritation or sensitization for various skin types.

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