Science
Mechanism of Action
Its action involves selectively stimulating nerve endings on the skin. Specifically, Menthyl Ethylamido Oxalate activates Transient Receptor Potential Melastatin 8 (TRPM8) channels, analogous to menthol, thereby modulating the perception of coolness.
Research
Clinical Evidence
High confidenceN/A
Transparency
Dusting Analysis
Information not available in provided research data.
The Formula
Formulation
Stability
This compound demonstrates excellent thermal stability, resisting degradation at temperatures up to 70°C. Optimal performance is observed in formulations with pH values ranging from acidic to neutral.
Conflicts
- Strong oxidizing agents
Safety
Safety Profile
Considered to possess an excellent safety profile, permitting its use as an active cosmetic ingredient globally, excluding China. GHS classification according to OSHA HCS indicates no hazard or precautionary statements. While generally well-tolerated, potential adverse reactions include mild skin irritation, sun sensitivity, or allergic reactions. Caution is advised to avoid application to sensitive areas, particularly the eyes.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Menthyl Ethylamido Oxalate is a valuable sensory enhancer, providing a scientifically validated, long-lasting cooling effect with excellent safety and broad formulation compatibility.
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