Science
Mechanism of Action
Mentha Piperita Leaf Extract functions by fortifying the skin's natural protective barrier, delivering antioxidant defense against free radicals, and stimulating microcirculation to enhance oxygen supply to skin cells. Its menthol component activates the cold-sensitive TRPM8 receptor, imparting a cooling sensation, alongside antibacterial effects, oil balance regulation, and inflammation reduction. Urtica Dioica Leaf Extract exhibits potent anti-inflammatory and antimicrobial actions, effectively calming irritated and blemish-prone skin. Rich in antioxidants, it safeguards against free radical damage and mitigates signs of aging. Its astringent qualities help tighten pores and refine skin texture, while also offering moisturizing properties and promoting wound healing. Furthermore, it can inhibit elastase and collagenase, contributing to its anti-aging efficacy.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Mentha Piperita Leaf Extract, at a 10% concentration, demonstrated negative results for skin irritation potential in an in vitro reconstructed human epidermis test. This concentration also significantly increased the dermal absorption of 14C-caffeine on porcine skin.
- 02 Urtica Dioica Extract effectively reduced reactive oxygen species (ROS) in H2O2-stimulated human skin fibroblasts, maintaining cell viability and protecting against H2O2-induced cytotoxicity without exhibiting cytotoxicity itself.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The optimal pH range for Mentha Piperita Leaf Extract is 4.5-6.5. The menthol component in peppermint can enhance the dermal penetration of other co-formulated active ingredients. This characteristic requires careful consideration for ingredients whose safety profiles are predicated on limited absorption.
Synergies
- Menthol component can enhance the dermal penetration of co-formulated active ingredients.
Safety
Safety Profile
Mentha Piperita (Peppermint) Leaf Extract is deemed safe for cosmetic use, with the critical restriction that its pulegone concentration must not exceed 1%. While generally safe and non-toxic, its high menthol content can potentially induce irritation in sensitive individuals or when used at elevated concentrations; patch testing is recommended. Urtica Dioica Extract is largely safe for cosmetic application, well-tolerated across most skin types, and considered non-comedogenic. Patch testing is nevertheless advisable for individuals with sensitive skin or a history of allergies.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This combined Mentha Piperita and Urtica Dioica Leaf Extract offers a multifaceted approach to skin health, providing antioxidant, anti-inflammatory, and conditioning benefits suitable for various skin types, making it a valuable ingredient for advanced skincare formulations.
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