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MENTHA PIPERITA LEAF JUICE.

Valuable CAS 84082-70-2 / SKIN CONDITIONING

Mentha Piperita Leaf Juice is a multi-functional botanical extract offering antioxidant, antimicrobial, and anti-inflammatory benefits to the skin. It provides a distinct cooling sensation and helps refine the appearance of oily and normal skin by acting as an astringent and promoting microcirculation.

Antioxidant Antimicrobial Antiseptic Anti-inflammatory Astringent Cooling Agent Microcirculation Enhancer Wound Healing Support Anti-aging Support Penetration Enhancer Skin Conditioning

Science

This ingredient functions as an antioxidant by neutralizing free radicals, thereby protecting skin from oxidative damage. Its antimicrobial and antiseptic properties support a healthy skin environment. As an anti-inflammatory agent, it aids in calming irritation and reducing redness. The characteristic cooling effect is primarily due to menthol, which activates the TRPM8 cold-sensitive channel. It also exhibits an astringent effect, assisting in tightening pores and balancing sebum production for oily skin types, and can enhance microcirculation for a brighter complexion. Furthermore, *in vitro* data suggests it can increase TGF-β gene expression to support wound healing and suppress ATP release from epidermal keratinocytes, potentially reducing dermal thinning and wrinkle formation. Menthol, a key component, may also enhance the skin penetration of other active ingredients.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro studies have demonstrated that Mentha Piperita Leaf Extract can increase TGF-β gene expression, which supports wound healing processes. It has also been shown to suppress ATP release from epidermal keratinocytes, suggesting a potential role in reducing dermal thinning and wrinkle formation.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 4 – 6.5
0 7 14

Stability

Optimal stability for Mentha Piperita Leaf Extract is reported within a pH range of 4.0 to 6.5.

Synergies

  • Menthol, a primary component, can enhance the transdermal penetration of other skincare ingredients, potentially boosting their efficacy.

Conflicts

  • Ingredients whose safety relies on limited systemic absorption should be carefully evaluated when combined with Mentha Piperita Leaf Juice due to menthol's penetration-enhancing properties.
  • High concentrations of this ingredient may cause irritation in individuals with sensitive skin, primarily due to its menthol content.

Safety

CIR Status
Safe with restrictions
Max tested
1%
Sensitization risk Moderate

Mentha Piperita Leaf Juice is deemed safe for cosmetic use by the CIR Expert Panel, provided that the concentration of pulegone, a natural constituent, does not exceed 1%. The U.S. FDA also recognizes it as Generally Recognized As Safe (GRAS) for food consumption. While *in vitro* tests showed Mentha Piperita Leaf Extract to be non-irritating at 10% and 100% concentrations, isolated clinical reports of irritation and/or sensitization to Peppermint Oil or its components have been documented. Formulators should be aware that menthol can enhance the penetration of other agents, necessitating careful safety assessment of co-ingredients.


Your Skin

Yes Normal
No Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Valuable

Mentha Piperita Leaf Juice is a valuable multi-functional ingredient offering significant antioxidant, anti-inflammatory, and cooling benefits, particularly suited for oily and normal skin, but requires careful formulation to adhere to pulegone concentration limits and manage potential irritation for sensitive individuals.


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