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Moumoujus

MENTHA PIPERITA AMERICAN HERB EXTRACT.

Valuable CAS 98306-02-6 / PERFUMING

Mentha Piperita American Herb Extract is a multi-functional botanical renowned for its anti-inflammatory, antioxidant, and wound-healing capabilities. It imparts a noticeable cooling and soothing sensation while effectively modulating oil production, rendering it particularly suitable for congested and oily skin profiles.

Summary

Antioxidant Anti-inflammatory Antimicrobial Soothing Cooling Wound Healing Oil Balancing Skin Conditioning Penetration Enhancer Perfuming

Science

Mechanism of Action

This extract operates by mitigating cellular damage and inhibiting lipid peroxidation through its inherent antioxidant properties. It actively reduces inflammation, calms irritation, and exhibits antimicrobial effects against various bacteria. The presence of constituents like menthol delivers an immediate cooling and soothing sensation upon application. Furthermore, it significantly contributes to wound repair by enhancing angiogenesis, shortening the inflammatory phase, and upregulating TGF-β gene expression. The extract also assists in regulating sebum secretion and minimizing pore blockage.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Mentha piperita essence demonstrated accelerated cutaneous wound healing in rats, attributed to increased TGF-β gene expression, reduced inflammatory duration, decreased inflammatory cells, and enhanced macrophage activity leading to greater angiogenesis.
  2. 02 Mentha piperita leaf extract suppressed the release of extracellular ATP (eATP) from epidermal keratinocytes, a mechanism implicated in the reduction of dermal thinning and wrinkle formation.
  3. 03 Topical application of a methanol leaf extract (2.0 mg/ear) of Mentha piperita on mice successfully reduced 12-O-tetradecanoylphorbol13-acetate-induced ear edema.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Synergies

  • The menthol component may enhance the percutaneous penetration of other active ingredients, potentially improving their efficacy.

Conflicts

  • Must be meticulously formulated to ensure a non-sensitizing profile, minimizing the risk of irritation or allergic reactions.
  • The penetration-enhancing properties of menthol must be carefully considered when co-formulating with other active ingredients, as it can influence their systemic absorption and safety assessments.

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that Mentha Piperita ingredients are safe for use in cosmetics and personal care products, provided they are formulated to be non-sensitizing. A critical consideration is ensuring that the concentration of pulegone, a naturally occurring component, does not exceed 1% in these ingredients. While the FDA lists peppermint as Generally Recognized As Safe (GRAS) for flavor, isolated clinical cases of irritation and/or sensitization have been reported, especially with peppermint oil. Formulators should also account for menthol's ability to enhance the dermal penetration of other active ingredients, which may necessitate adjustments to safety evaluations of the final product.

Your Skin

Skin Compatibility

No Normal
No Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Mentha Piperita American Herb Extract is a valuable ingredient due to its proven anti-inflammatory, antioxidant, and oil-balancing benefits, offering substantial support for problematic skin and contributing to dermal rejuvenation when carefully formulated to mitigate potential sensitization.

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