Science
Mechanism of Action
This extract functions as a skin conditioning agent, actively contributing to the maintenance of healthy skin. Its antioxidant capabilities stem from constituents like gallic acid and rutin, which neutralize free radicals. Furthermore, in vitro studies indicate its capacity to inhibit Matrix Metalloproteinase-1 (MMP-1) expression in UVA-irradiated human dermal fibroblasts, suggesting it may prevent the breakdown of crucial extracellular matrix proteins, thereby supporting anti-photoaging efforts.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
No specific data is available regarding the 'dusting' of Melothria Heterophylla Root Extract, nor are there established thresholds for its concentration in this context.
The Formula
Formulation
Stability
Specific optimal pH range data for the stability of Melothria Heterophylla Root Extract is not readily available. As an extract, it is typically prepared using solvents like water or ethanol.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not conducted a specific safety assessment for Melothria Heterophylla Root Extract. However, it is noted by EWG as having low concerns for cancer, allergies/immunotoxicity, and developmental/reproductive toxicity. No specific SCCS opinion or FDA cosmetic ingredient approval status has been identified. Acute toxicity studies in mice, involving oral administration, showed no mortality at doses up to 2000 mg/kg, suggesting a favorable safety profile in that context.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Melothria Heterophylla Root Extract is a valuable ingredient, offering significant antioxidant and potential anti-photoaging benefits based on its established mechanisms, despite the current absence of human clinical studies.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources