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MELISSA OFFICINALIS LEAF/STEM OIL.

Valuable CAS 84082-61-1 (generic); 8014-71-9 (generic) / FRAGRANCE, SKIN CONDITIONING - MISCELLANEOUS

Melissa Officinalis Leaf/Stem Oil is a multi-functional botanical extract, rich in tannins and polyphenols, known for its extensive skin benefits. It offers potent antimicrobial, antioxidant, and anti-inflammatory properties, addressing a range of concerns from breakouts to signs of aging. This versatile oil also exhibits astringent qualities, aiding in sebum balance and pore refinement.

Summary

Antioxidant Antimicrobial Antiviral Antifungal Astringent Soothing Sebum-regulating Skin renewal Elasticity enhancement Masking Perfuming

Science

Mechanism of Action

Upon topical application, MELISSA OFFICINALIS LEAF/STEM OIL delivers antiviral, antibacterial, and antifungal actions primarily through its tannin and polyphenol components, combating various skin pathogens. It functions as an antioxidant by neutralizing free radicals, thereby mitigating oxidative stress associated with skin aging. The oil provides soothing and anti-inflammatory benefits to calm irritated skin, while its astringent properties help regulate sebum production, tighten pores, and manage oiliness. Furthermore, it actively combats acne-causing bacteria and supports skin renewal and elasticity, attributed to its content of flavonoids and vitamins.

Research

Clinical Evidence

Medium confidence
Effective range 1.5–200%
Optimal

N/A

Key findings

  1. 01 Demonstrated high virucidal activity against Herpes Simplex Virus type 1 (HSV-1) at 1.5 μg/mL in vitro.
  2. 02 Inhibited the replication of Herpes Simplex Virus type 2 (HSV-2) in HEp-2 cells at concentrations from 25 to 200 μg/mL in vitro.
  3. 03 Proven effective (when formulated in a cream) for the therapy of herpes simplex labialis in a double-blind, placebo-controlled trial, significantly shortening healing time and preventing infection spread.

Transparency

Dusting Analysis

Not commonly dusted

As an oil-based ingredient, Melissa Officinalis Leaf/Stem Oil is not typically prone to dusting in formulations.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

While generally well-tolerated in personal care, Melissa Officinalis Leaf Oil contains fragrant components, such as citronellal, geranial, and neral (constituting 50-70% of the oil). These can potentially cause skin irritation or allergic reactions in sensitive individuals, especially at higher concentrations. Dilution in a carrier oil and patch testing are advised to mitigate risk.

Your Skin

Skin Compatibility

No Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

This botanical oil delivers a broad spectrum of benefits, including significant antimicrobial, antioxidant, soothing, and sebum-regulating properties, making it a valuable addition for diverse skin concerns, though its fragrant nature warrants cautious application for sensitive skin.

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