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Moumoujus

MELILOTUS OFFICINALIS FLOWER EXTRACT.

Valuable CAS 84082-81-5 / ASTRINGENT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Melilotus Officinalis Flower Extract is a botanical powerhouse, providing significant anti-inflammatory and antioxidant benefits to the skin. It actively works to enhance microcirculation and promote tissue regeneration, making it a valuable asset for maintaining skin health and combating signs of aging.

Summary

Anti-inflammatory Antioxidant Astringent Skin conditioning Emollient Microcirculation enhancer Tissue regenerator Soothing Masking Perfuming

Science

Mechanism of Action

This extract mitigates inflammation by reducing circulating phagocytes and lowering citrulline production. Its comprehensive action is attributed to a rich profile of bioactive compounds, including coumarin, p-coumaric acid, gallic acid, and quercetin, which collectively contribute to its anti-inflammatory and antioxidant capabilities. Beyond these, it functions to optimize microcirculation, decrease capillary permeability, boost tissue oxygen supply, inhibit elastase and lipase activity, and stimulate fibroblast production, all essential for preventing skin aging and supporting regeneration.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

2%

Key findings

  1. 01 A 2% concentration demonstrated remarkable inflammation reduction, mirroring the efficacy of hydrocortisone, without inducing adverse skin reactions in preclinical rat models.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 5.15 – 7.15
0 7 14

Stability

Formulations, specifically creams and gels containing the extract, demonstrated stable physical characteristics over a 6-month period when stored at room temperature (22 ± 2 °C). Observed pH values for the cream formulation ranged from 5.15 to 5.98, while the gel maintained a pH between 7.15 and 6.88.

Conflicts

  • Contains coumarin, a recognized fragrance allergen, which can potentially induce allergic contact dermatitis in susceptible individuals. The presence of high levels of coumarin impurities may further elevate the risk of skin sensitization.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
5%
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) has not yet evaluated Melilotus Officinalis Flower Extract. The European Union (EU) mandates the declaration of coumarin, a natural constituent of this extract (typically 0.3%, up to 5% in certain extracts), as a fragrance allergen at concentrations exceeding 10 ppm in leave-on products and 100 ppm in rinse-off products, owing to its potential for sensitization. While preclinical studies in rat models using 2% formulations did not report adverse skin reactions, the ingredient carries a risk of allergic contact dermatitis in sensitive individuals due to its coumarin content. Its FDA status for cosmetic application remains undefined.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Melilotus Officinalis Flower Extract is a valuable ingredient offering significant anti-inflammatory, antioxidant, and microcirculation-enhancing benefits, though its coumarin content necessitates careful consideration for individuals with sensitive skin.

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