Science
Mechanism of Action
This extract combats oxidative stress by efficiently scavenging free radicals, a function attributed to its high concentration of phenols, flavonoids, anthocyanins, and ellagitannins. Its antimicrobial action targets a broad spectrum of skin pathogens, including Staphylococcus aureus and Propionibacterium acne, by interfering with bacterial cell walls and disrupting microbial membranes. Furthermore, it supports skin regeneration through promoting fibroblast cell proliferation and increasing collagen fiber thickness, alongside offering potential anti-inflammatory and skin-brightening effects by reducing discoloration.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Various Melastoma candidum extracts (water, acetone, ethanol, ethyl acetate) demonstrated good antibacterial activity against B. subtilis, S. aureus, E. coli, and P. aeruginosa. The acetone extract, in particular, showed notable effectiveness within a concentration range of 62.5-125.0 µg/mL.
- 02 An ethanolic extract of Melastoma candidum leaves, formulated as a gel, significantly increased the number of fibroblast cells and the thickness of collagen fibers in socket wounds of male white rats following tooth extraction, suggesting strong wound healing potential.
Transparency
Dusting Analysis
Information regarding 'dusting' practices or specific low efficacy thresholds for Melastoma candidum extract is not available in the provided research data.
The Formula
Formulation
Stability
Polyphenols within Melastoma candidum leaves are polar compounds, demonstrating relative stability in acidic environments and good solubility in polar solvents such as ethanol and methanol. For optimal emulsion stability, particularly with related species like Melastoma malabathricum, lower temperatures (e.g., 4°C) and a pH around 6 are indicated as beneficial.
Safety
Safety Profile
While Melastoma malabathricum, a closely related species, has shown general safety in acute and subchronic toxicity studies, specific Cosmetic Ingredient Review (CIR), SCCS, or FDA safety statuses for Melastoma candidum extract in cosmetic applications are not currently available.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Melastoma candidum extract presents itself as a valuable multi-functional ingredient due to its robust antioxidant, antimicrobial, and wound-healing capabilities, showing broad compatibility across various skin types.
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