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MEDICAGO SATIVA EXTRACT.

Valuable CAS 84082-36-0 / TONIC

Medicago Sativa Extract, derived from the Alfalfa plant, is a sophisticated botanical active recognized for its retinol-like properties. It actively diminishes wrinkles by enhancing collagen production and hindering its breakdown, while also delivering comprehensive soothing, antioxidant, and skin barrier-strengthening benefits for refined skin health.

Anti-aging Wrinkle reduction Collagen booster Antioxidant Skin barrier support Anti-inflammatory Soothing Improves microcirculation Skin firming Cell regeneration Brightening Tonic

Science

This extract operates as a retinol-mimetic, stimulating dermal metabolism to effectively combat visible wrinkles. It significantly boosts Type I collagen synthesis and inhibits matrix metalloproteinase-1 (MMP-1), an enzyme responsible for degrading the extracellular matrix, including collagen and elastin. Rich in galactomannans, it provides anti-aging effects without typical irritation. Its chlorophyll content offers antioxidant protection and nourishment, while amino acids reinforce the skin's structure and barrier function, reducing sensitivity. Flavonoids and saponins further strengthen the barrier and mitigate inflammation. The ingredient also enhances microcirculation for a healthier complexion, promotes tight junction formation, and accelerates epidermal cell differentiation, with potential anti-melanogenic activity.


Research

High confidence
Effective range 0.5–10%
Optimal

N/A

Key findings

  1. 01 Recommended as an optimal cosmetic use level for achieving anti-aging and soothing benefits, typically incorporated into water-based formulations.
  2. 02 In vivo studies demonstrated significant wrinkle reduction after 28 days of treatment, attributed to its ability to stimulate collagen I synthesis and inhibit MMP-1 activity.
  3. 03 In vitro testing on skin cells revealed increased proliferation and metabolic activity; specifically, a 2.5% concentration boosted keratinocyte viability by over 170%, and highest concentrations resulted in approximately 150% increase in fibroblast viability.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Stable for up to one year under standard storage conditions, with optimal stability between 23-25°C, tolerating a range of 16-32°C. Freezing should be avoided, as well as extreme heat.

Conflicts

  • strong oxidizers

Safety

CIR Status
Not reviewed
Sensitization risk Low

Generally regarded as a safe cosmetic ingredient without specific restrictions from European regulatory bodies. The FDA classifies Medicago Sativa (Alfalfa) extract as 'Generally Recognized As Safe' (GRAS) for food applications. Individuals with documented legume allergies should proceed with caution and conduct a patch test due to potential sensitivity.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Medicago Sativa Extract is a valuable botanical active, offering retinol-like anti-aging benefits, potent antioxidant protection, and comprehensive skin barrier support across all skin types with a low risk of irritation.


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