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MARRUBIUM VULGARE EXTRACT.

Valuable CAS 84696-20-8 / SKIN CONDITIONING, SOOTHING

Marrubium Vulgare Extract, derived from white horehound, is a multi-functional botanical celebrated for its robust antioxidant and anti-inflammatory properties. This extract is adept at calming distressed skin, refining its texture, and bolstering its natural defenses against environmental damage.

Antioxidant Soothing Emollient Anti-acne Skin-protecting

Science

This extract operates through a complex blend of bioactive compounds, including diterpenes like Marrubiin, which deliver anti-inflammatory effects, and phenolic acids such as chlorogenic acid and phenylethanoids, providing potent antioxidant and antimicrobial benefits. Flavonoids further contribute to its antioxidant and anti-inflammatory profile. Together, these components shield the skin from free radicals, reduce irritation, strengthen the skin barrier, and promote healthy cellular regeneration and wound healing by enhancing fibroblast proliferation and cell migration.


Research

High confidence
Effective range 1–3%
Optimal

2.5%

Key findings

  1. 01 Demonstrated anti-histaminic, anti-inflammatory, wound healing, antifungal, and antimicrobial effects in topical applications.
  2. 02 Improved skin moisture and restored a healthy glow within one hour of topical application. After four weeks, it reduced blackheads and refined rough skin texture.
  3. 03 Twice-daily topical application for 28 days reduced skin roughness by up to 50% and graininess by up to 34%.
  4. 04 After four weeks of twice-daily topical application, the color and size of comedones were reduced by up to 52%, with their total number decreasing by up to 93%.
  5. 05 Exhibited the strongest antioxidant effect on fibroblasts and keratinocytes in vitro by significantly decreasing intracellular reactive oxygen species.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The extract exhibits good stability in aqueous formulations and is commonly dissolved in glycerin and water. Its phenolic components maintain solubility in polar solvents.


Safety

CIR Status
Not reviewed
Sensitization risk Low

In vitro studies confirm no cytotoxicity to skin cells (BJ fibroblasts and HaCaT keratinocytes) at concentrations up to 10.0%. EWG Skin Deep classifies Marrubium Vulgare Extract as 'Restricted' for EWG VERIFIED products without specific substantiation.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Marrubium Vulgare Extract is a valuable, versatile ingredient offering robust antioxidant protection, anti-inflammatory benefits, and significant improvements in skin texture and clarity, suitable for all skin types.


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