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MANGIFERA INDICA SEED GLYCERIDES.

Valuable / EMULSION STABILISING, SKIN CONDITIONING, SKIN PROTECTING, VISCOSITY CONTROLLING

Mangifera Indica Seed Glycerides, derived from mango seed, function as a potent emollient and nourishing agent for the skin. They are integral in forming a protective barrier that effectively minimizes moisture loss, leading to a smoother, more supple complexion. Furthermore, these glycerides contribute to reducing the visible signs of skin aging, such as fine lines and wrinkles.

Summary

Emollient Moisturizing Antioxidant Anti-aging Skin-conditioning

Science

Mechanism of Action

Mangifera Indica Seed Glycerides, as primary components of mango seed oil, operate as a multifaceted emollient, moisturizing, and nourishing ingredient. They deliver a rich blend of essential amino acids, powerful antioxidant phenolic compounds including ferulic acid, and beneficial fatty acids such as stearic and oleic acid to the skin. These constituents cooperatively establish an occlusive barrier on the skin's surface, significantly reducing transepidermal water loss. This mechanism enhances skin hydration, improves suppleness, and refines skin texture. Additionally, their robust antioxidant capacity helps to neutralize free radicals, thereby mitigating premature aging symptoms.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Mango lipid, when precisely formulated into nanostructured lipid carriers (NLCs), demonstrated an impressive 92.60% ± 0.87% in vitro drug release over 24 hours. This advanced formulation also achieved approximately 86.35% ex vivo skin permeation, significantly outperforming a comparative marketed product. Gels incorporating mango lipid maintained acceptable physical properties with a gradual release profile.
  2. 02 Mangifera indica L. extract, delivered via nanolipid carriers (M-NLCs), exhibited enhanced antioxidant and anti-aging efficacy. This was substantiated through comprehensive in vitro, ex vivo (rat skin), and in vivo (human volunteer) studies, underscoring its potential as a strategic treatment for oxidative stress and skin aging.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH 6.8 – 7.1
0 7 14

Stability

Formulations containing mango lipid, specifically gels, have demonstrated acceptable stability within a pH range of 6.8 to 7.1.

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel concluded that related ingredients, including Mangifera Indica (Mango) Seed Oil and Butter, and Sodium Mangoseedate, are safe for use in cosmetic products. This determination was based on their history of safe food use, detailed compositional analysis, and evidence confirming they are not dermal irritants or sensitizers.

Your Skin

Skin Compatibility

No Normal
Yes Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Mangifera Indica Seed Glycerides are a valuable emollient and antioxidant ingredient, highly effective at moisturizing dry skin, reinforcing the skin barrier, and demonstrating potential anti-aging benefits, particularly when incorporated into advanced delivery systems.

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